About: Diarylsulfonylurea Compound     Goto   Sponge   Distinct   Permalink

An Entity of Type : owl:Class, within Data Space : linked.opendata.cz associated with source document(s)

AttributesValues
rdf:type
rdfs:label
  • Diarylsulfonylurea Compound
rdfs:subClassOf
Semantic_Type
  • Chemical Viewed Structurally
Preferred_Name
  • Diarylsulfonylurea Compound
UMLS_CUI
  • C1511894
Legacy_Concept_Name
  • Diarylsulfonylurea_Compound
FULL_SYN
  • Diarylsulfonylurea CompoundPTNCI
  • DiarylsulfonylureasSYNCI
DEFINITION
  • A sulfonylurea compound containing aryl groups with potential antineoplastic activity. Originally developed as herbicides, diarylsulfonylureas have shown a broad spectrum of antitumor activity in vivo. The precise mechanism of antitumor action has not yet been elucidated, however, certain diarylsulfonylurea compounds have been shown in preliminary studies to exert antimitotic effects through their inhibition of tubulin polymerization, and others have been shown to be effective antitumor agents in animal models by the mechanism of uncoupling mitochondrial oxidative phosphorylation.NCI
code
  • C2186
is rdfs:subClassOf of
Faceted Search & Find service v1.16.118 as of Jun 21 2024


Alternative Linked Data Documents: ODE     Content Formats:   [cxml] [csv]     RDF   [text] [turtle] [ld+json] [rdf+json] [rdf+xml]     ODATA   [atom+xml] [odata+json]     Microdata   [microdata+json] [html]    About   
This material is Open Knowledge   W3C Semantic Web Technology [RDF Data] Valid XHTML + RDFa
OpenLink Virtuoso version 07.20.3240 as of Jun 21 2024, on Linux (x86_64-pc-linux-gnu), Single-Server Edition (126 GB total memory, 18 GB memory in use)
Data on this page belongs to its respective rights holders.
Virtuoso Faceted Browser Copyright © 2009-2024 OpenLink Software