About: WFDC1 Protein     Goto   Sponge   Distinct   Permalink

An Entity of Type : owl:Class, within Data Space : linked.opendata.cz associated with source document(s)

AttributesValues
rdf:type
rdfs:label
  • WFDC1 Protein
rdfs:subClassOf
OMIM_Number
  • 605322
Semantic_Type
  • Amino Acid, Peptide, or Protein
  • Biologically Active Substance
Preferred_Name
  • WFDC1 Protein
UMLS_CUI
  • C1439195
Legacy_Concept_Name
  • WFDC1_Protein
FULL_SYN
  • WFDC1 ProteinPTNCI
  • WFDC1SYNCI
  • Prostate Stromal Protein ps20SYNCI
  • WAP Four-Disulfide Core Domain 1 ProteinSYNCI
Swiss_Prot
  • Q9HC57
DEFINITION
  • Encoded by human WFDC1 Gene, the 220-amino acid 24 kD (precursor) secretory Prostate Stromal Protein ps20 (WAP Family) is a growth inhibitor that contains a WAP four-disulfide core domain characteristic of protease inhibitors. The WAP signature motif contains eight cysteines forming four disulfide bonds at the core of proteins that functions as a protease inhibitor in many family members. Human ps20 shares approximately 86% and 88% identity with the rat and mouse secreted growth inhibitor proteins. Loss of ps20 is associated with prostate, breast, and hepatocellular cancers and Wilms' tumor. (from SWISS-PROT, OMIM, Proteome, and NCI)NCI
code
  • C21536
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