About: Complement C3

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An Entity of Type : owl:Class, within Data Space : linked.opendata.cz associated with source document(s)

Attributes	Values
rdf:type	Class
rdfs:label	Complement C3
equivalentClass	nodeID://b631605
OMIM_Number	120700
Semantic_Type	Amino Acid, Peptide, or Protein
Preferred_Name	Complement C3
UMLS_CUI	C0009506
Legacy_Concept_Name	Complement_Component-3
FULL_SYN	C3SYNCI Complement Component 3SYNCI Complement C3PTNCI C3 and PZP-Like Alpha-2-Macroglobulin Domain-Containing Protein 1SYNCI
Swiss_Prot	P01024
DEFINITION	Complement C3 (1663 aa, ~187 kDa) is encoded by the human C3 gene. This protein plays a role in complement-mediated immunity.NCI
DesignNote	Complement Component 3, encoded by the C3 gene plays a central role in the activation of complement system. Its activation is required for both classical and alternative complement activation pathways. People with C3 deficiency are susceptible to bacteria infection. (From LocusLink) Complement C3 is cleaved into the following 10 chains: Complement C3 beta chain, Complement C3 alpha chain, C3a anaphylatoxin, Complement C3b alpha' chain, Complement C3c alpha' chain fragment 1, Complement C3dg fragment, Complement C3g fragment, Complement C3d fragment, Complement C3f fragment, and Complement C3c alpha' chain fragment 2. (UniProt)
code	C21527
sameAs	Complement C3
http://linked.open...y/mesh/hasConcept	http://linked.opendata.cz/resource/mesh/concept/M0004928
is sameAs of	Complement C3 Complement C3

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