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AttributesValues
rdf:type
rdfs:label
  • ORC Subunit Gene
rdfs:subClassOf
Semantic_Type
  • Gene or Genome
Preferred_Name
  • ORC Subunit Gene
UMLS_CUI
  • C1335089
Legacy_Concept_Name
  • ORC_Subunit_Gene
FULL_SYN
  • ORC Subunit GenePTNCI
DEFINITION
  • DNA replication is initiated by the Origin Recognition Complex (ORC). ORC is composed of six protein subunits and binds to the ARS Consensus Sequence (ACS) of Origins of Replication in an ATP-dependent manner. While ORC remains bound to origins throughout the cell cycle, the binding of ORC and other factors modulates local chromatin structure to facilitate replication initiation. All 6 genes encoding ORC (ORC1 through ORC6) may be required for initiation of DNA replication and are essential for viability.NCI
code
  • C20371
is rdfs:subClassOf of
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