About: SWI2/SNF2     Goto   Sponge   Distinct   Permalink

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AttributesValues
rdf:type
rdfs:label
  • SWI2/SNF2
rdfs:subClassOf
Semantic_Type
  • Amino Acid, Peptide, or Protein
  • Biologically Active Substance
Preferred_Name
  • SWI2/SNF2
UMLS_CUI
  • C1335886
Legacy_Concept_Name
  • SWI2-SNF2_Protein
FULL_SYN
  • Regulatory Protein GAM1SYNCI
  • Regulatory Protein SWI2SYNCI
  • Mating Type Switch 2/Sucrose Nonfermenting 2SYNCI
  • Transcription Factor TYE3SYNCI
  • Transcription Regulatory Protein SNF2SYNCI
  • Snf2pSYNCI
  • Swi2pSYNCI
  • SWI/SNF Complex Component SNF2SYNCI
  • SWI2/SNF2PTNCI
Swiss_Prot
  • P22082
DEFINITION
  • Nuclear SWI2/SNF2 (SNF2/RAD54 Helicase Family) is a 1703-aa, 194-kD general RNA polymerase II transcription regulator component of the SWI/SNF nucleosome/chromatin remodeling complex involved in global transcriptional activation of induced gene expression and coordinate regulation of phospholipid synthesis. This complex alters chromatin structure to facilitate binding of gene-specific transcription factors. Containing a bromodomain domain and three AT Hook DNA-binding repeats, SWI2/SNF2 exhibits strong similarity to Drosophila brahma. (from Swiss-Prot, and NCI)NCI
DesignNote
  • Protein_Has_Structural_Domain_Or_Motif: Bromodomain Domain, AT Hook DNA-Binding Repeats
  • Protein_Encoded_by_Gene: SNF2
  • Protein_Family: SNF2/RAD54 Helicase Family
  • Protein_Is_Physical_Part_Of: SWI/SNF
  • SGDID S0005816
code
  • C19803
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