About: Oncogene FPS-FES     Goto   Sponge   Distinct   Permalink

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AttributesValues
rdf:type
rdfs:label
  • Oncogene FPS-FES
equivalentClass
OMIM_Number
  • 190030
GenBank_Accession_Number
  • X06292
Semantic_Type
  • Gene or Genome
Preferred_Name
  • Oncogene FPS-FES
UMLS_CUI
  • C0812383
Legacy_Concept_Name
  • Oncogene_FPS-FES
FULL_SYN
  • FESSYNCI
  • Oncogene FESSYNCI
  • FPSSYNCI
  • Oncogene FPS-FESPTNCI
  • Fujinami Sarcoma Virus and Feline Sarcoma Virus Transforming GeneSYNCI
Gene_Encodes_Product
  • FPS-FES Oncoprotein
DEFINITION
  • Human Oncogene FPS-FES is a mutated variant of FES Gene (FES/FPS Subfamily), which encodes 822 aa 93-kDa Tyrosine-Protein Kinase FES/FPS, a tyrosine-specific protein kinase involved in normal hematopoiesis and containing an FCH and SH2 domain. The FES chromosomal location is linked to a translocation identified in patients with acute promyelocytic leukemia. A truncated transcript is generated utilizing a start site in a far downstream exon. Oncogene FPS-FES disrupts normal cell function.NCI
code
  • C18453
is someValuesFrom of
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