About: TFIID

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An Entity of Type : owl:Class, within Data Space : linked.opendata.cz associated with source document(s)

Attributes	Values
rdf:type	Class
rdfs:label	TFIID
rdfs:subClassOf	Transcription Factors, General Protein or Riboprotein Complex nodeID://b717547 nodeID://b717548 nodeID://b717549
Semantic_Type	Amino Acid, Peptide, or Protein
Preferred_Name	TFIID
UMLS_CUI	C0076919
Legacy_Concept_Name	TFIID
FULL_SYN	Transcription Factor IIDSYNCI TF2DSYNCI TFIIDPTNCI
DEFINITION	TFIID is a DNA-binding protein complex required for RNA polymerase II-mediated transcription of many, if not all, protein-encoding genes in eukaryotic cells. TFIID plays a key role in initiation, since it binds to the TATA element to form a complex that nucleates the assembly of the other components into a preinitiation complex. TFIID interacts with TFIIA, which may stabilize its binding. A reinitiation intermediate including TFIID can act as a scaffold for formation of a functional reinitiation complex. TFIID also links the control of transcription to the cell cycle. The DNA-binding subunit of TFIID is the TATA box-binding protein (TBP) that interacts primarily within the minor groove of the DNA helix. The largest subunit of TFIID is TAF1, which can autophosphorylate and transphosphorylate the large subunit of the basal factor TFIIF. (From OMIM and NCI)NCI
code	C17540
sameAs	Transcription Factor TFIID
http://linked.open...y/mesh/hasConcept	http://linked.opendata.cz/resource/mesh/concept/M0159351
is someValuesFrom of	nodeID://b716933 nodeID://b717082 nodeID://b717104 nodeID://b717128 nodeID://b717132 nodeID://b717136 nodeID://b717138 nodeID://b717144 nodeID://b717146 nodeID://b717152 nodeID://b717156 nodeID://b717160 nodeID://b717164 nodeID://b717169 nodeID://b717173 nodeID://b717180 nodeID://b718944
is sameAs of	Transcription Factor TFIID Transcription Factor TFIID

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