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An Entity of Type : owl:Class, within Data Space : linked.opendata.cz associated with source document(s)

AttributesValues
rdf:type
rdfs:label
  • P-Selectin
equivalentClass
OMIM_Number
  • 173610
Semantic_Type
  • Amino Acid, Peptide, or Protein
Preferred_Name
  • P-Selectin
UMLS_CUI
  • C0134835
Legacy_Concept_Name
  • P-Selectin
FULL_SYN
  • CD62SYNCI
  • SELPSYNCI
  • GMP140SYNCI
  • GMP-140SYNCI
  • P-SelectinPTNCI
Swiss_Prot
  • P16109
DEFINITION
  • P-selectin (830 aa, 91 kD) is a cell adhesion process protein that is encoded by the human SELP gene and has a role in cell adhesion.NCI
DesignNote
  • P-Selectin is a cell surface adhesion molecule that mediates the interaction of activated endothelial cells or platelets with neutrophils and monocytes. The protein is detected in megakaryocytes and platelets, as well as in vascular endothelial cells, but not in other cell types. In endothelia, the protein is localized to the membranes of Weibel-Palade bodies, intracellular storage granules for von Willebrand factor. CD24 is a ligand for P-selectin. Sorting nexin-17 interacts with the cytosolic domain of P-selectin and may function in the intracellular trafficking of P-selectin.
  • Cell adhesion molecule and CD antigen that mediates the adhesion of neutrophils and monocytes to activated platelets and endothelial cells.
code
  • C17522
sameAs
http://linked.open...y/mesh/hasConcept
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