About: DNA Polymerase Delta     Goto   Sponge   Distinct   Permalink

An Entity of Type : owl:Class, within Data Space : linked.opendata.cz associated with source document(s)

AttributesValues
rdf:type
rdfs:label
  • DNA Polymerase Delta
rdfs:subClassOf
Semantic_Type
  • Amino Acid, Peptide, or Protein
  • Enzyme
Preferred_Name
  • DNA Polymerase Delta
UMLS_CUI
  • C0012890
Legacy_Concept_Name
  • DNA_Polymerase_Delta
FULL_SYN
  • DNA Polymerase Delta ComplexSYNCI
  • DNA Polymerase DeltaPTNCI
  • Delta DNA PolymeraseSYNCI
DEFINITION
  • A protein complex that has dual enzymatic activities in DNA synthesis. The enzyme complex both facilitates DNA synthesis by acting as a polymerase and exhibits exonuclease activity that degrades single stranded DNA in the 3' to 5' direction. It is a heterotetramer comprised of the DNA polymerase delta catalytic subunit and 3 DNA polymerase delta accessory subunits.NCI
DesignNote
  • DNA polymerase delta interaction with the proliferating cell nuclear antigen and the multisubunit replication factor C is essential for leading strand synthesis. (UniProt)
code
  • C16511
sameAs
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