About: Daunorubicin Hydrochloride

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Attributes	Values
rdf:type	Class
rdfs:label	Daunorubicin Hydrochloride
rdfs:subClassOf	Anthracyclines
Has_Free_Acid_Or_Base_Form	DAUNORUBICIN
Concept_In_Subset	FDA Established Names and Unique Ingredient Identifier Codes Terminology
Semantic_Type	Pharmacologic Substance
Preferred_Name	Daunorubicin Hydrochloride
NSC_Code	82151 83142
UMLS_CUI	C0701062
CAS_Registry	23541-50-6
Accepted_Therapeutic_Use_For	Acute Lymphoblastic Leukemia; Acute Myeloid Leukemia
FDA_UNII_Code	UD984I04LZ
Contributing_Source	FDA
ALT_DEFINITION	A drug used to treat acute leukemias and some other types of cancer. It blocks a certain enzyme needed for cell division and DNA repair, and it may kill cancer cells. Cerubidine is a type of anthracycline antibiotic and a type of topoisomerase inhibitor.NCI-GLOSS
PDQ_Open_Trial_Search_ID	39779
PDQ_Closed_Trial_Search_ID	39779
Chemical_Formula	C27H29NO10.HCl
Legacy_Concept_Name	Daunomycin
FULL_SYN	CerubidinePTNCI-GLOSSCDR0000583858 RubidomycinBRNCI 5,12-Naphthacenedione, 8-acetyl-10-[(3-amino-2,3,6-trideoxy-.alpha.-L-lyxo-hexopyranosyl)oxy]-7,8,9,10-tetrahydro-6,8,11-trihydroxy-1-methoxy-, hydrochloride, (8S-cis)-(9CI)SNNCI Daunorubicin hydrochlorideSYDTPNSC0083142 daunomycin hydrochloridePTNCI-GLOSSCDR0000632152 DaunoblastinFBNCI 5,12-Naphthacenedione, 8-acetyl-10-[(3-amino-2,3,6-trideoxy-.alpha.-L-lyxo-hexopyranosyl)oxy]-7,8,9,10-tetrahydro-6,8,11-trihydroxy-1-methoxy-, (8S-cis)-, hydrochlorideSNNCI DaunoblastinaFBNCI DaunoblastineSYNCI Daunomycin HydrochlorideSYNCI Rubidomycin HydrochlorideSYNCI Daunorubicin HydrochloridePTNCI daunorubicin hydrochloridePTNCI-GLOSSCDR0000583859 Cloridrato de DaunorubicinaSYNCI OndenaFBNCI Daunorubicini HydrochloridumSYNCI FI-6339CNNCI RubilemFBNCI CERUBIDINESYDTPNSC0082151 RP-13057CNNCI DAUNORUBICIN HYDROCHLORIDEPTFDAUD984I04LZ Daunomycin hydrochlorideSYDTPNSC0082151 L-lyxo-Hexopyranoside, 3.beta.-acetyl-1,2,3,4,6,11-hexahydro-3,5,12-trihydroxy-10-metldioxo-1a-naphthacenyl 3-amino-2,3,6-trideoxy-,.alpha.-,hydrochlorideSNNCI CerubidinFBNCI Daunomycin, hydrochlorideSYDTPNSC0083142 Daunorubicin.HClPTDCP01604 CerubidineBRNCI
DEFINITION	The hydrochloride salt of an anthracycline antineoplastic antibiotic with therapeutic effects similar to those of doxorubicin. Daunorubicin exhibits cytotoxic activity through topoisomerase-mediated interaction with DNA, thereby inhibiting DNA replication and repair and RNA and protein synthesis.NCI
code	C1583
sameAs	Daunorubicin Hydrochloride
http://linked.open...y/mesh/hasConcept	http://linked.opendata.cz/resource/mesh/concept/M0361544
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