About: Trioxifene Mesylate     Goto   Sponge   Distinct   Permalink

An Entity of Type : owl:Class, within Data Space : linked.opendata.cz associated with source document(s)

AttributesValues
rdf:type
rdfs:label
  • Trioxifene Mesylate
rdfs:subClassOf
Has_Free_Acid_Or_Base_Form
Concept_In_Subset
Semantic_Type
  • Organic Chemical
  • Pharmacologic Substance
Preferred_Name
  • Trioxifene Mesylate
UMLS_CUI
  • C0146868
CAS_Registry
  • 68307-81-3
FDA_UNII_Code
  • 63ZD22G88L
Contributing_Source
  • FDA
Chemical_Formula
  • C30H31NO3.CH4O3S
Legacy_Concept_Name
  • Trioxifene_Mesylate
FULL_SYN
  • Compound 133314SYNCI
  • Trioxifene MesilateSYNCI
  • Trioxifene MesylatePTNCI
  • LY-133314CNNCI
  • TRIOXIFENE MESYLATEPTFDA63ZD22G88L
  • 3,4-Dihydro-2-(p-methoxyphenyl)-1-naphthyl p-(2-(1-pyrrolidinyl)ethoxy)phenyl Ketone MethanesulfonateSNNCI
DEFINITION
  • A mesylate salt form of trioxifene, a nonsteroidal selective estrogen receptor modulator (SERM). Trioxifene competitively inhibits the binding of estradiol to estrogen receptor alpha (ER alpha), resulting in ER alpha-mediated gene expression. Clinical development of Trioxifene has not proceeded because of lack of superior results over tamoxifen and side effect profile. (NCI)NCI
code
  • C1414
http://linked.open...y/mesh/hasConcept
is Has_Salt_Form of
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