About: Prednisolone Sodium Succinate

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An Entity of Type : owl:Class, within Data Space : linked.opendata.cz associated with source document(s)

Attributes	Values
rdf:type	Class
rdfs:label	Prednisolone Sodium Succinate
rdfs:subClassOf	Therapeutic Glucocorticoid
Concept_In_Subset	FDA Established Names and Unique Ingredient Identifier Codes Terminology
Semantic_Type	Pharmacologic Substance Steroid
Preferred_Name	Prednisolone Sodium Succinate
NSC_Code	9151
UMLS_CUI	C0138274
CAS_Registry	1715-33-9
FDA_UNII_Code	8223RR9DWF
Contributing_Source	FDA
Chemical_Formula	C25H31O8.Na
Legacy_Concept_Name	Prednisolone_Sodium_Succinate
FULL_SYN	PREDNISOLONE SODIUM SUCCINATEPTFDA8223RR9DWF Prednisolone sodium succinateSYDTPNSC0009151 Prednisolone Sodium SuccinatePTNCI Precortalon AquosumFBNCI
DEFINITION	The sodium succinate salt form of prednisolone, a synthetic glucocorticoid with anti-inflammatory and immunomodulating properties. After cell surface receptor attachment and cell entry, prednisolone enters the nucleus where it binds to and activates specific nuclear receptors, resulting in an altered gene expression and inhibition of proinflammatory cytokine production. This agent also decreases the number of circulating lymphocytes, induces cell differentiation, and stimulates apoptosis in sensitive tumor cells populations. (NCI)NCI
code	C1403
http://linked.open...y/mesh/hasConcept	http://linked.opendata.cz/resource/mesh/concept/M0076033

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