About: Beta-Thioguanine Deoxyriboside     Goto   Sponge   Distinct   Permalink

An Entity of Type : owl:Class, within Data Space : linked.opendata.cz associated with source document(s)

AttributesValues
rdf:type
rdfs:label
  • Beta-Thioguanine Deoxyriboside
rdfs:subClassOf
Semantic_Type
  • Pharmacologic Substance
  • Nucleic Acid, Nucleoside, or Nucleotide
Preferred_Name
  • Beta-Thioguanine Deoxyriboside
NSC_Code
  • 71261
UMLS_CUI
  • C0053376
CAS_Registry
  • 64039-27-6
  • 789-61-7
PDQ_Open_Trial_Search_ID
  • 39711
PDQ_Closed_Trial_Search_ID
  • 39711
Legacy_Concept_Name
  • Beta-Thioguanine_Deoxyriboside
FULL_SYN
  • 6H-Purine-6-thione, 2-amino-9-(2-deoxy-.beta.-D-erythro-pentofuranosyl)-1,9-dihydro-SYDTPNSC0071261
  • 9H-Purine-6-thiol, 2-amino-9-(2-deoxy-.beta.-D-erythro-pentofuranosyl)-, monohydrateSYDTPNSC0071261
  • 9H-purine-6-thiol, 2-amino-9-(2-deoxy-beta-D-erythro-pentofuranosyl) monohydrateSNNCI
  • 1,9-dihydro-6H-purine-6-thione, 2-amino-9-(2-deoxy-beta-D-erythro-pentofuranosyl)SNNCI
  • .beta.-2'-DeoxythioguanosineSYDTPNSC0071261
  • 2'-desoxy-6-thioguanosineSNNCI
  • 2'-DeoxythioguanosineSYDTPNSC0071261
  • BTGABNCI
  • beta-2'-deoxythioguanosineSNNCI
  • thioguanine 9-.beta-D-2'-deoxyribosideSNNCI
  • .beta.-2'-Deoxythiol guanosineSYDTPNSC0071261
  • Thioguanine 9.beta.D-2'-deoxyribosideSYDTPNSC0071261
  • beta-2'-deoxythiol guanosineSNNCI
  • B-TGDRABNCI
  • .beta.-2'-Deoxy-6-thioguanosineSYDTPNSC0071261
  • beta-2'-deoxy-6-thioguanosineSNNCI
  • 6-MercaptoguaninedeoxyribosideSYDTPNSC0071261
  • Beta Thioguanine DeoxyribosideSYNCI
  • Beta-Thioguanine DeoxyribosidePTNCI
  • 6-MercaptoguaninedeoxyribosideSNNCI
  • 2'-Desoxy-6-thioguanosineSYDTPNSC0071261
  • .beta.-Thioguanine deoxyribosideSYDTPNSC0071261
  • 2'-deoxythioguanosineSNNCI
DEFINITION
  • A thiopurine nucleoside derivative with antineoplastic activity. After conversion to the triphosphate, beta-thioguanine deoxyriboside is incorporated into DNA, resulting in inhibition of DNA replication. This agent is cytotoxic against leukemia cell lines and has demonstrated some activity against leukemia cells in vivo. Beta-thioguanine deoxyriboside demonstrates antineoplastic activity against 6-thioguanine-resistant tumor cells. (NCI04)NCI
code
  • C1350
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