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An Entity of Type : owl:Class, within Data Space : linked.opendata.cz associated with source document(s)

AttributesValues
rdf:type
rdfs:label
  • Tributyrin
equivalentClass
Concept_In_Subset
Semantic_Type
  • Lipid
  • Pharmacologic Substance
Preferred_Name
  • Tributyrin
NSC_Code
  • 661583
UMLS_CUI
  • C0077025
CAS_Registry
  • 60-01-5
FDA_UNII_Code
  • S05LZ624MF
Contributing_Source
  • FDA
ALT_DEFINITION
  • A triglyceride drug that may inhibit cell growth and induce cell differentiation. Differentiating agents may be effective in changing cancer cells back into normal cells.NCI-GLOSS
PDQ_Open_Trial_Search_ID
  • 42290
PDQ_Closed_Trial_Search_ID
  • 42290
Chemical_Formula
  • C15H26O6
Legacy_Concept_Name
  • Tributyrin
FULL_SYN
  • TributyrinPTNCI
  • Butanoic Acid, 1,2,3-Propanetriyl EsterPTDCP04044
  • tributyrinPTNCI-GLOSSCDR0000045443
  • 1,2,3-TributyrylglycerolSNNCI
  • Glyceryl tributyrateSYDTPNSC0661583
  • TBABNCI
  • Butanoic Acid 1,2,3-Propanetriyl EsterSNNCI
  • 1,2,3-Propanetriyl ButanoateSNNCI
  • 1,2,3-TributyrylglycerolSYDTPNSC0661583
  • TRIBUTYRINPTFDAS05LZ624MF
  • Butyryl TriglycerideSYNCI
  • Glyceryl TributyrateSYNCI
  • TributyrinSYDTPNSC0661583
DEFINITION
  • A triglyceride prodrug of butyric acid with potential antineoplastic activity. Butyrate, the active metabolite of tributyrin, inhibits histone deacetylase, resulting in increased differentiation, decreased proliferation, cell cycle arrest, and apoptosis in some tumor cell lines. (NCI04)NCI
code
  • C1260
http://linked.open...y/mesh/hasConcept
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