About: Exemestane

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An Entity of Type : owl:Class, within Data Space : linked.opendata.cz associated with source document(s)

Attributes	Values
rdf:type	Class
rdfs:label	Exemestane
rdfs:subClassOf	Steroidal Aromatase Inhibitor
Concept_In_Subset	FDA Established Names and Unique Ingredient Identifier Codes Terminology
Semantic_Type	Pharmacologic Substance Steroid
Preferred_Name	Exemestane
NSC_Code	713563
UMLS_CUI	C0851344
CAS_Registry	107868-30-4
Accepted_Therapeutic_Use_For	Estrogen Receptor-Positive Early Breast Cancer; early and advanced-stage breast cancer
In_Clinical_Trial_For	Breast cancer
FDA_UNII_Code	NY22HMQ4BX
Contributing_Source	FDA
ALT_DEFINITION	A drug used to treat advanced breast cancer and to prevent recurrent breast cancer in postmenopausal women who have already been treated with tamoxifen. It is also being studied in the treatment of other types of cancer. Aromasin causes a decrease in the amount of estrogen made by the body. It is a type of aromatase inhibitor.NCI-GLOSS
PDQ_Open_Trial_Search_ID	42297
PDQ_Closed_Trial_Search_ID	42297
Chemical_Formula	C20H24O2
Legacy_Concept_Name	Exemestane
CHEBI_ID	CHEBI:4953
FULL_SYN	exemestanePTNCI-GLOSSCDR0000045445 ExemestanePTDCP20117 6-Methyleneandrosta-1,4-diene-3,17-dioneSNNCI EXEMESTANEPTFDANY22HMQ4BX AromasinPTNCI-GLOSSCDR0000508683 AromasinBRNCI FCE-24304CNNCI ExemestaneSYDTPNSC0713563 ExemestanePTNCI
DEFINITION	A synthetic androgen analogue. Exemestane binds irreversibly to and inhibits the enzyme aromatase, thereby blocking the conversion of cholesterol to pregnenolone and the peripheral aromatization of androgenic precursors into estrogens. (NCI04)NCI
code	C1097
sameAs	EXEMESTANE EXEMESTANE
http://linked.open...y/mesh/hasConcept	http://linked.opendata.cz/resource/mesh/concept/M0158502
is someValuesFrom of	nodeID://b650381 nodeID://b658244 nodeID://b671419 nodeID://b671421 nodeID://b671423 nodeID://b671425
is sameAs of	EXEMESTANE EXEMESTANE EXEMESTANE EXEMESTANE

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