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An Entity of Type : owl:Class, within Data Space : linked.opendata.cz associated with source document(s)

AttributesValues
rdf:type
rdfs:label
  • Clarithromycin
rdfs:subClassOf
Concept_In_Subset
Semantic_Type
  • Antibiotic
  • Carbohydrate
Preferred_Name
  • Clarithromycin
NSC_Code
  • 643733
UMLS_CUI
  • C0055856
CAS_Registry
  • 81103-11-9
Accepted_Therapeutic_Use_For
  • H. pylori infection; Various bacterial infections
FDA_UNII_Code
  • H1250JIK0A
Contributing_Source
  • FDA
ALT_DEFINITION
  • An antibiotic drug used to treat infection. It belongs to the family of drugs called macrolides.NCI-GLOSS
PDQ_Open_Trial_Search_ID
  • 42308
PDQ_Closed_Trial_Search_ID
  • 42308
Chemical_Formula
  • C38H69NO13
Legacy_Concept_Name
  • Clarithromycin
CHEBI_ID
  • CHEBI:3732
FULL_SYN
  • 6-O-MethylerythromycinSNNCI
  • Abbott-56268SYNCI
  • CLARITHROMYCINPTFDAH1250JIK0A
  • ClarithromycinPTNCI
  • ClarithromycinSYDTPNSC0643733
  • BiaxinBRNCI
  • clarithromycinPTNCI-GLOSSCDR0000045449
  • ClarithromycinPTDCP09601
DEFINITION
  • A semisynthetic 14-membered ring macrolide antibiotic. Clarithromycin binds to the 50S ribosomal subunit and inhibits RNA-dependent protein synthesis in susceptible organisms. Clarithromycin has been shown to eradicate gastric MALT (mucosa-associated lymphoid tissue) lymphomas, presumably due to the eradication of tumorigenic Helicobacter pylori infection. This agent also acts as a biological response modulator, possibly inhibiting angiogenesis and tumor growth through alterations in growth factor expression. (NCI04)NCI
code
  • C1054
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