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  • Podle studie MWS je ve srovnání s ženami, které HST nikdy neužívaly, užívání různých typů kombinované estrogen/progestagenové léčby spojeno s vyšším rizikem rakoviny prsu (RR = 2,00, 95%CI:1,88 – 2,12) oproti léčbě samotnými estrogeny (RR = 1,30, 95%CI:1,21 – 1,40) nebo léčbě tibolonem (RR = 1,45;95%CI 1,25 – 1,68). (cs)
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