About: Ellagic Acid     Goto   Sponge   Distinct   Permalink

An Entity of Type : http://linked.opendata.cz/ontology/drugbank/Drug, within Data Space : linked.opendata.cz associated with source document(s)

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http://linked.open...gbank/description
  • Ellagic acid is present in several fruits such as cranberries, strawberries, raspberries, and pomegranates. In pomegranates, there are several therapeutic compounds but ellagic acid is the most active and abundant. Ellagic acid is also present in vegetables. Ellagic acid is an investigational drug studied for treatment of Follicular Lymphoma (phase 2 trial), protection from brain injury of intrauterine growth restricted babies (phase 1 and 2 trial), improvement of cardiovascular function in adolescents who are obese (phase 2 trial), and topical treatment of solar lentigines. Ellagic acid's therapeutic action mostly involves antioxidant and anti-proliferative effects. (en)
http://linked.open...generalReferences
  • # Seeram NP, Lee R, Heber D: Bioavailability of ellagic acid in human plasma after consumption of ellagitannins from pomegranate (Punica granatum L.) juice. Clin Chim Acta. 2004 Oct;348(1-2):63-8. "Pubmed":http://www.ncbi.nlm.nih.gov/pubmed/15369737 # The Merck Index monographs (en)
http://linked.open...gy/drugbank/group
  • investigational (en)
http://linked.open...ugbank/indication
  • Ellagic acid is being investigated for use in follicular lymphoma, brain injury in intrauterine growth restricted babies, obese adolescents, and solar lentigines. (en)
sameAs
Title
  • Ellagic Acid (en)
adms:identifier
http://linked.open...mechanismOfAction
  • The exact mechanism of action of ellagic acid in its different potential indications is still being investigated. (en)
http://linked.open...ynthesisReference
  • A)Nierenstein M: The Formation of Ellagic Acid from Galloyl-Glycine by Penicillium. Biochem J. 1915 Jun;9(2):240-4. B)Löwe, Zeitschrift für Chemie, 1868, 4, 603. (en)
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  • After oral consumption, ellagic acid reaches maximum concentrations in about 1 hour. (en)
http://linked.open.../affectedOrganism
  • Humans and other mammals (en)
http://linked.open...casRegistryNumber
  • 476-66-4 (en)
http://linked.open...drugbank/category
  • (en)
http://linked.open...rugbank/clearance
  • Ellagic acid is eliminated from the body in about 4 hours. (en)
http://linked.open...k/Bioavailability
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