| Attributes | Values |
|---|
| rdf:type
| |
| http://linked.open...gbank/description
| - NGX-4010 is a NeurogesX's novel high-concentration trans-capsaicin dermal patch. (en)
|
| http://linked.open...generalReferences
| - # Simpson DM, Estanislao L, Brown SJ, Sampson J: An Open-Label Pilot Study of High-Concentration Capsaicin Patch in Painful HIV Neuropathy. J Pain Symptom Manage. 2007 Oct 22;. "Pubmed":http://www.ncbi.nlm.nih.gov/pubmed/17959343 (en)
|
| http://linked.open...gy/drugbank/group
| |
| http://linked.open...ugbank/indication
| - Investigated for use/treatment in neurologic disorders, pain (acute or chronic), and post herpetic neuralgia. (en)
|
| sameAs
| |
| Title
| |
| adms:identifier
| |
| http://linked.open...mechanismOfAction
| - NGX-4010 is a topical, physician administered patch containing a high concentration of trans-capsaicin, a synthetic form of the naturally occurring capsaicin and the ingredient that makes chili peppers hot. The patch is designed to act peripherally, or in the skin, where the pain frequently originates, unlike current treatment approaches for neuropathic pain that include opioids and other agents acting on the central nervous system that can cause drowsiness or other systemic side effects. Due to the novel patch delivery system and dermal site of action of NGX-4010, the potential for safety issues or side effects that negatively impact quality of life is expected to be low. (en)
|
| http://linked.open...ugbank/IUPAC-Name
| |
| http://linked.open...gy/drugbank/InChI
| |
| http://linked.open...Molecular-Formula
| |
| http://linked.open.../Molecular-Weight
| |
| http://linked.open...noisotopic-Weight
| |
| http://linked.open...y/drugbank/SMILES
| |
| http://linked.open.../Water-Solubility
| |
| http://linked.open...ogy/drugbank/logP
| |
| http://linked.open...ogy/drugbank/logS
| |
| http://linked.open...nd-Acceptor-Count
| |
| http://linked.open...-Bond-Donor-Count
| |
| http://linked.open...drugbank/InChIKey
| |
| http://linked.open...urface-Area--PSA-
| |
| http://linked.open...nk/Polarizability
| |
| http://linked.open...bank/Refractivity
| |
| http://linked.open...atable-Bond-Count
| |
| http://linked.open...drugbank/category
| |
| http://linked.open...k/Bioavailability
| |
| http://linked.open...bank/Ghose-Filter
| |
| http://linked.open...nk/MDDR-Like-Rule
| |
| http://linked.open...k/Number-of-Rings
| |
| http://linked.open...siological-Charge
| |
| http://linked.open...bank/Rule-of-Five
| |
| http://linked.open...tional-IUPAC-Name
| |
| http://linked.open...strongest-acidic-
| |
| http://linked.open...-strongest-basic-
| |
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