About: Cholestyramine

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An Entity of Type : http://linked.opendata.cz/ontology/drugbank/Drug, within Data Space : linked.opendata.cz associated with source document(s)

Attributes	Values
rdf:type	http://linked.opendata.cz/ontology/drugbank/Drug
http://linked.open...gbank/description	Cholestyramine or colestyramine is a bile acid sequestrant. Bile acid sequestrants are polymeric compounds which serve as ion exchange resins. Cholestyramine resin is quite hydrophilic, but insoluble in water. (en)
http://linked.open...y/drugbank/dosage	http://linked.opendata.cz/resource/drugbank/dosage/271B4A4F-363D-11E5-9242-09173F13E4C5 http://linked.opendata.cz/resource/drugbank/dosage/271B4A50-363D-11E5-9242-09173F13E4C5 http://linked.opendata.cz/resource/drugbank/dosage/271B4A51-363D-11E5-9242-09173F13E4C5 http://linked.opendata.cz/resource/drugbank/dosage/271B4A52-363D-11E5-9242-09173F13E4C5
http://linked.open...gy/drugbank/group	approved (en)
http://linked.open...drugbank/halfLife	6 minutes (en)
http://linked.open...ugbank/indication	Indicated as adjunctive therapy to diet for the reduction of elevated serum cholesterol in patients with primary hypercholesterolemia (elevated low density lipoprotein [LDL] cholesterol) who do not respond adequately to diet. Also for the relief of pruritus associated with partial biliary obstruction. (en)
sameAs	Cholestyramine Cholestyramine
Title	Cholestyramine (en)
adms:identifier	http://linked.opendata.cz/resource/drugbank/drug/DB01432/identifier/drugbank/DB01432 http://linked.opendata.cz/resource/drugbank/drug/DB01432/identifier/national-drug-code-directory/0185-0940-97 http://linked.opendata.cz/resource/drugbank/drug/DB01432/identifier/pharmgkb/PA448974 http://linked.opendata.cz/resource/drugbank/drug/DB01432/identifier/wikipedia/Cholestyramine
http://linked.open...mechanismOfAction	Cholestyramine binds bile in the gastrointestinal tract to prevent its reabsorption. The resin is a strong anion exchange resin, which means that it can exchange its chloride anions with anionic bile acids in the gastrointestinal tract and bind them strongly in the resin matrix. The functional group of the anion exchange resin is a quaternary ammonium group attached to an inert styrene-divinylbenzene copolymer. (en)
http://linked.open...drugbank/packager	Ivax pharmaceuticals inc sub teva pharmaceuticals usa Bristol-Myers Squibb Co. Caremark LLC Abbott laboratories hosp products div Abraxis pharmaceutical products Astrazeneca lp Baxter healthcare corp anesthesia and critical care Direct Dispensing Inc. DispenseXpress Inc. Dispensing Solutions Diversified Healthcare Services Inc.
http://linked.open...outeOfElimination	Cholestyramine resin adsorbs and combines with the bile acids in the intestine to form an insoluble complex which is excreted in the feces. (en)
http://linked.open.../drugbank/synonym	Colestyramine (en) Cholestyramine resin (en)
http://linked.open...drugbank/toxicity	Overdose may result in blockage of intestine or stomach. (en)
http://linked.open.../drug/hasAHFSCode	http://linked.opendata.cz/resource/AHFS/24-06-04
http://linked.open...k/foodInteraction	Take with food, do not mix with soft drinks. (en)
http://linked.open...ynthesisReference	Moh. S. Amer, Jack C. Gray, "Cholestyramine compositions and method for preparation thereof." U.S. Patent US4895723, issued March, 1967. (en)
http://linked.open...y/mesh/hasConcept	http://linked.opendata.cz/resource/mesh/concept/M0004278
foaf:page	http://www.drugs.com/cdi/cholestyramine-powder.html http://www.rxlist.com/cgi/generic/cholestyramine.htm
http://linked.open.../Water-Solubility	http://linked.opendata.cz/resource/drugbank/property/271B4A53-363D-11E5-9242-09173F13E4C5
http://linked.open...l/drug/hasATCCode	Colestyramine
http://linked.open...ugbank/absorption	Not absorbed from the gastrointestinal tract following oral administration. (en)
http://linked.open.../affectedOrganism	Humans and other mammals (en)
http://linked.open...casRegistryNumber	11041-12-6 (en)
http://linked.open...drugbank/category	(en)
http://linked.open...gbank/containedIn	Arixtra (0.5 Ml Syringe) 2.5 mg/syr Syringe Arixtra 2.5 mg/0.5ml Solution 0.5ml Syringe Arixtra 7.5 mg/0.6ml Solution 0.6ml Syringe Pms-Cholestyramine Light 4 g Powder Packet Pms-Cholestyramine Regular 4 g Powder Packet Prevalite packet Cholestyramine light packet Cholestyramine Light 4 gm Packets Cholestyramine 4 gm Packets Dopamine 40 mg/ml vial Questran light packet Questran 4 gm Packets Cholestyramine resin powder Cholestyramine 4 gm/dose Powder 378 gm Can Cholestyramine Light 4 gm/dose Powder 210 gm Can

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