About: Inulin

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About: Inulin Goto Sponge Distinct Permalink

An Entity of Type : http://linked.opendata.cz/ontology/drugbank/Drug, within Data Space : linked.opendata.cz associated with source document(s)

Attributes	Values
rdf:type	http://linked.opendata.cz/ontology/drugbank/Drug
http://linked.open...gbank/description	A starch found in the tubers and roots of many plants. Since it is hydrolyzable to fructose, it is classified as a fructosan. It has been used in physiologic investigation for determination of the rate of glomerular function. [PubChem] (en)
http://linked.open...generalReferences	# Abrams SA, Griffin IJ, Hawthorne KM, Liang L, Gunn SK, Darlington G, Ellis KJ: A combination of prebiotic short- and long-chain inulin-type fructans enhances calcium absorption and bone mineralization in young adolescents. Am J Clin Nutr. 2005 Aug;82(2):471-6. "Pubmed":http://www.ncbi.nlm.nih.gov/pubmed/16087995 # Coudray C, Demigne C, Rayssiguier Y: Effects of dietary fibers on magnesium absorption in animals and humans. J Nutr. 2003 Jan;133(1):1-4. "Pubmed":http://www.ncbi.nlm.nih.gov/pubmed/12514257 # Coussement PA: Inulin and oligofructose: safe intakes and legal status. J Nutr. 1999 Jul;129(7 Suppl):1412S-7S. "Pubmed":http://www.ncbi.nlm.nih.gov/pubmed/10395609 # Roberfroid MB: Introducing inulin-type fructans. Br J Nutr. 2005 Apr;93 Suppl 1:S13-25. "Pubmed":http://www.ncbi.nlm.nih.gov/pubmed/15877886 (en)
http://linked.open...gy/drugbank/group	approved (en) nutraceutical (en)
http://linked.open...drugbank/halfLife	2-4 hours (en)
http://linked.open...ugbank/indication	Historically used in an important medical test of renal function, specifically a measure of glomerular filtration rate. Sometimes used to help relieve symptoms of diabetes mellitus - a condition characterised by hyperglycemia and/or hyperinsulinemia. (en)
http://linked.open...bank/manufacturer	App pharmaceuticals llc
sameAs	Inulin Inulin
Title	Inulin (en)
adms:identifier	http://linked.opendata.cz/resource/drugbank/drug/DB00638/identifier/chebi/15443 http://linked.opendata.cz/resource/drugbank/drug/DB00638/identifier/chemspider/23149 http://linked.opendata.cz/resource/drugbank/drug/DB00638/identifier/drugbank/DB00638 http://linked.opendata.cz/resource/drugbank/drug/DB00638/identifier/kegg-compound/C03323 http://linked.opendata.cz/resource/drugbank/drug/DB00638/identifier/kegg-drug/D00171 http://linked.opendata.cz/resource/drugbank/drug/DB00638/identifier/pharmgkb/PA450043 http://linked.opendata.cz/resource/drugbank/drug/DB00638/identifier/pubchem-compound/24763 http://linked.opendata.cz/resource/drugbank/drug/DB00638/identifier/pubchem-substance/46508287 http://linked.opendata.cz/resource/drugbank/drug/DB00638/identifier/wikipedia/Inulin
http://linked.open...mechanismOfAction	As a diagnostic agent, inulin is readily soluble and essentially indigestible. It readily passes through the blood and into the urine. It is neither secreted nor resorbed by the kidney making it an excellent indicator for renal clearance rates. The inulin clearance test has largely been succeeded by the creatinine clearance test as a measure of glomerular filtration rate. As a hypoglycemic agent, inulin is not digestible by human enzymes ptyalin and amylase, which are designed to digest starch. As a result, inulin passes through much of the digestive system intact. It is only in the colon that bacteria metabolise inulin, with the release of significant quantities of carbon dioxide and/or methane. Because inulin is not broken down into simple sugars (monosaccharides) by normal digestion, it does not elevate blood sugar levels, hence, helping diabetics regulate blood sugar levels. (en)
http://linked.open...drugbank/packager	Ben Venue Laboratories Inc. Accord healthcare inc usa
http://linked.open...nk/proteinBinding	None (en)
http://linked.open...ynthesisReference	Ernst Hoehn, Curtis J. McKay, E. Donald Murray, "Production of high fructose syrup from inulin involving ultrafiltration." U.S. Patent US4421852, issued July, 1981. (en)
foaf:page	http://www.drugs.com/cons/inulin-intravenous.html http://www.pdrhealth.com/drug_info/nmdrugprofiles/nutsupdrugs/inu_0299.shtml
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http://linked.open...ugbank/absorption	Poorly absorbed, passes through to urine unmetabolized (en)
http://linked.open.../affectedOrganism	Humans and other mammals (en)
http://linked.open...casRegistryNumber	9005-80-5 (en)
http://linked.open...drugbank/category	(en)
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