About: Hyoscyamine

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An Entity of Type : http://linked.opendata.cz/ontology/drugbank/Drug, within Data Space : linked.opendata.cz associated with source document(s)

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rdf:type	http://linked.opendata.cz/ontology/drugbank/Drug
http://linked.open...gbank/description	Hyoscyamine is a chemical compound, a tropane alkaloid it is the levo-isomer to atropine. It is a secondary metabolite of some plants, particularly henbane (Hyoscamus niger.) Hyoscyamine is used to provide symptomatic relief to various gastrointestinal disorders including spasms, peptic ulcers, irritable bowel syndrome, pancreatitis, colic and cystitis. It has also been used to relieve some heart problems, control some of the symptoms of Parkinson's disease, as well as for control of respiratory secretions in end of life care. (en)
http://linked.open...gy/drugbank/group	approved (en)
http://linked.open...drugbank/halfLife	2-3.5 hours (en)
http://linked.open...ugbank/indication	For treatment of bladder spasms, peptic ulcer disease, diverticulitis, colic, irritable bowel syndrome, cystitis, and pancreatitis. Also used to treat certain heart conditions, to control the symptoms of Parkinson's disease and rhinitis. (en)
sameAs	Hyoscyamine Hyoscyamine
Title	Hyoscyamine (en)
adms:identifier	http://linked.opendata.cz/resource/drugbank/drug/DB00424/identifier/chebi/17486 http://linked.opendata.cz/resource/drugbank/drug/DB00424/identifier/drugbank/DB00424 http://linked.opendata.cz/resource/drugbank/drug/DB00424/identifier/kegg-compound/C02046 http://linked.opendata.cz/resource/drugbank/drug/DB00424/identifier/kegg-drug/D00147 http://linked.opendata.cz/resource/drugbank/drug/DB00424/identifier/pharmgkb/PA164776844 http://linked.opendata.cz/resource/drugbank/drug/DB00424/identifier/wikipedia/Hyoscyamine
http://linked.open...mechanismOfAction	Hyoscyamine competes favorably with acetylcholine for binding at muscarinic receptors in the salivary, bronchial, and sweat glands as well as in the eye, heart, and gastrointestinal tract. The actions of hyoscyamine result in a reduction in salivary, bronchial, gastric and sweat gland secretions, mydriasis, cycloplegia, change in heart rate, contraction of the bladder detrusor muscle and of the gastrointestinal smooth muscle, and decreased gastrointestinal motility. (en)
http://linked.open...drugbank/packager	Breckenridge Pharmaceuticals Advanced Pharmaceutical Services Inc. Advanced Pharmaceutical Services Inc. AG Marin Pharmaceuticals Alaven Pharmaceutical Palmetto Pharmaceuticals Inc. Alphagen Laboratories Inc. Amerifit Inc. Amerisource Health Services Corp. Pharmaceutical Utilization Management Program VA Inc. Actavis Group Cardinal Health Aidarex Pharmacuticals LLC Amerisource Health Services Corp. Apotex Inc. AQ Pharmaceuticals Inc. A-S Medication Solutions LLC Atlantic Biologicals Corporation Biovail Pharmaceuticals Bryant Ranch Prepack Sandoz Cardinal Health Catalent Pharma Solutions Dispensing Solutions Comprehensive Consultant Services Inc. Corepharma LLC Coupler Enterprises Inc. Dept Health Central Pharmacy Direct Dispensing Inc. Direct Pharmaceuticals Inc. Dispensing Solutions Diversified Healthcare Services Inc. DSM Corp. Actavis elizabeth llc Inwood laboratories inc sub forest laboratories inc Global Pharmaceuticals Golden State Medical Supply Inc. Amerisource Health Services Corp. AQ Pharmaceuticals Inc. App pharmaceuticals llc Baxter healthcare corp anesthesia critical care Amerifit Inc. Amerisource Health Services Corp. Amkas Laboratories Inc. Amneal Pharmaceuticals Apotheca Inc. Contract Pharm Corepharma LLC CVS Pharmacy Direct Dispensing Inc. Dispensing Solutions Diversified Healthcare Services Inc. Edwards Pharmaceuticals Sandoz H.J. Harkins Co. Inc. Johnson & Johnson Healthcare Alcon Laboratories Aristos Pharmaceuticals Atlantic Biologicals Corporation Alcon inc Pfizer Inc. Atlantic Biologicals Corporation Actavis elizabeth llc Apotex inc etobicoke site Breckenridge Pharmaceuticals Ivax pharmaceuticals inc sub teva pharmaceuticals usa Comprehensive Consultant Services Inc. Ivax pharmaceuticals inc sub teva pharmaceuticals usa
http://linked.open.../drugbank/synonym	Hyoscyamine (en) (S)-(−)-hyoscyamine (en) (S)-atropine (en) (−)-atropine (en) (−)-hyoscyamine (en) Daturine (en) Duboisine (en) L-Hyoscyamine (en) L-Tropine Tropate (en) (-)-Atropine (en) (-)-Hyoscyamine (en) (S)-(-)-Hyoscyamine (en) Daturin (en) Hyoscyamin (en) Hyoscyaminum (en) Tropine, (-)-tropate (en) Tropine-L-tropate (en)

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