About: Menotropins

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An Entity of Type : http://linked.opendata.cz/ontology/drugbank/Drug, within Data Space : linked.opendata.cz associated with source document(s)

Attributes	Values
rdf:type	http://linked.opendata.cz/ontology/drugbank/Drug
http://linked.open...gbank/description	Menotropins contains follicle stimulating hormone (FSH) and luteinizing hormone (LH) purified from the urine of postmenopausal women. It is used as a fertility medication that is injected either subcutaneously or intramuscularly. It is composed of LH with 2 subunits, alpha = 92 residues, beta = 121 residues and FSH with 2 subunits, alpha = 92 residues, beta=111 residues. (en)
http://linked.open...y/drugbank/dosage	http://linked.opendata.cz/resource/drugbank/dosage/271B40A5-363D-11E5-9242-09173F13E4C5 http://linked.opendata.cz/resource/drugbank/dosage/271B40A6-363D-11E5-9242-09173F13E4C5 http://linked.opendata.cz/resource/drugbank/dosage/271B40A7-363D-11E5-9242-09173F13E4C5
http://linked.open...gy/drugbank/group	approved (en)
http://linked.open...ugbank/indication	For the treatment of female infertility (en)
sameAs	Menotropins Menotropins
Title	Menotropins (en)
adms:identifier	http://linked.opendata.cz/resource/drugbank/drug/DB00032/identifier/drugbank/DB00032 http://linked.opendata.cz/resource/drugbank/drug/DB00032/identifier/genbank/X00264 http://linked.opendata.cz/resource/drugbank/drug/DB00032/identifier/uniprotkb/P01229 http://linked.opendata.cz/resource/drugbank/drug/DB00032/identifier/pharmgkb/PA164749406 http://linked.opendata.cz/resource/drugbank/drug/DB00032/identifier/wikipedia/Menotropins
http://linked.open...mechanismOfAction	Being a combination drug, Menotropins bind to the Follicle stimulating hormone receptor (which results in ovulation in the absence of sufficient endogenous Luteinizing hormone)and It also binds to the LH receptor, thereby stimulating proper hormone release. The drug contains both FSH and LH,therefore, it induces ovarian follicular growth and development as well as gonadal steroid production in women who do not have ovarian failure.FSH is the primary driver of follicular recruitment and growth in early folliculogenesis, while LH is important for ovarian steroidogenesis and is involved in the physiological events leading to development of a competent pre-ovulatory follicle (en)
http://linked.open...drugbank/packager	Ferring Pharmaceuticals Inc.
http://linked.open.../drug/hasAHFSCode	http://linked.opendata.cz/resource/AHFS/68-18-00
http://linked.open...y/mesh/hasConcept	http://linked.opendata.cz/resource/mesh/concept/M0013384
foaf:page	http://www.drugs.com/cdi/menotropins.html http://www.rxlist.com/cgi/generic/menotropins.htm
http://linked.open...Molecular-Formula	http://linked.opendata.cz/resource/drugbank/property/271B40AC-363D-11E5-9242-09173F13E4C5
http://linked.open.../Molecular-Weight	http://linked.opendata.cz/resource/drugbank/property/271B40AB-363D-11E5-9242-09173F13E4C5
http://linked.open.../affectedOrganism	Humans and other mammals (en)
http://linked.open...casRegistryNumber	61489-71-2 (en)
http://linked.open...drugbank/category	(en)
http://linked.open...gbank/containedIn	Menopur 75 unit vial Repronex 75 unit vial Repronex 5 75 unit Solution 1 Box Contains Five 1ml Vials
http://linked.open...nk/Hydrophobicity	http://linked.opendata.cz/resource/drugbank/property/271B40A9-363D-11E5-9242-09173F13E4C5
http://linked.open...Isoelectric-Point	http://linked.opendata.cz/resource/drugbank/property/271B40AA-363D-11E5-9242-09173F13E4C5
http://linked.open...ank/Melting-Point	http://linked.opendata.cz/resource/drugbank/property/271B40A8-363D-11E5-9242-09173F13E4C5

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