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Description
| - Increased levels of vitamin D may protect against colorectal cancer (CRC) development and recurrence. Accumulating epidemiologic evidence suggests these effects may be partly mediated by genetic variants of the vitamin D receptor (VDR) proposed to be associated with altered risk of CRC. We wished to determine if common VDR polymorphisms affected CRC risk in the Czech Republic, a homogenous European population with a high CRC incidence rate. We conclude that common variation in the VDR gene had little effect on its own on predisposition to sporadic CRC in the Czech population.
- Increased levels of vitamin D may protect against colorectal cancer (CRC) development and recurrence. Accumulating epidemiologic evidence suggests these effects may be partly mediated by genetic variants of the vitamin D receptor (VDR) proposed to be associated with altered risk of CRC. We wished to determine if common VDR polymorphisms affected CRC risk in the Czech Republic, a homogenous European population with a high CRC incidence rate. We conclude that common variation in the VDR gene had little effect on its own on predisposition to sporadic CRC in the Czech population. (en)
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Title
| - Variation in the vitamin D receptor gene is not associated with colorectal cancer in the Czech Republic
- Variation in the vitamin D receptor gene is not associated with colorectal cancer in the Czech Republic (en)
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skos:prefLabel
| - Variation in the vitamin D receptor gene is not associated with colorectal cancer in the Czech Republic
- Variation in the vitamin D receptor gene is not associated with colorectal cancer in the Czech Republic (en)
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skos:notation
| - RIV/75010330:_____/11:00009221!RIV12-GA0-75010330
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http://linked.open...avai/predkladatel
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http://linked.open...avai/riv/aktivita
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http://linked.open...avai/riv/aktivity
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http://linked.open...iv/cisloPeriodika
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http://linked.open...vai/riv/dodaniDat
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http://linked.open...aciTvurceVysledku
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http://linked.open.../riv/druhVysledku
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http://linked.open...iv/duvernostUdaju
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http://linked.open...titaPredkladatele
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http://linked.open...dnocenehoVysledku
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http://linked.open...ai/riv/idVysledku
| - RIV/75010330:_____/11:00009221
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http://linked.open...riv/jazykVysledku
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http://linked.open.../riv/klicovaSlova
| - colorectal cancer; vitamin D; prevention (en)
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http://linked.open.../riv/klicoveSlovo
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http://linked.open...odStatuVydavatele
| - US - Spojené státy americké
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http://linked.open...ontrolniKodProRIV
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http://linked.open...i/riv/nazevZdroje
| - Journal of gastrointestinal cancer
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http://linked.open...in/vavai/riv/obor
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http://linked.open...ichTvurcuVysledku
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http://linked.open...cetTvurcuVysledku
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http://linked.open...vavai/riv/projekt
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http://linked.open...UplatneniVysledku
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http://linked.open...v/svazekPeriodika
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http://linked.open...iv/tvurceVysledku
| - Vodičková, Ludmila
- Souček, Pavel
- Hlavatá, Ivona
- Hughes, D. J.
- Jenab, M.
- Naccarati, A.
- Pardini, B.
- Vodička, P.
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issn
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number of pages
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is http://linked.open...avai/riv/vysledek
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