About: Ionotropic NMDA and P2X1/5 receptors mediate synaptically induced Ca2+ signalling in cortical astrocytes

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About: Ionotropic NMDA and P2X1/5 receptors mediate synaptically induced Ca2+ signalling in cortical astrocytes Goto Sponge Distinct Permalink

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rdf:type	skos:Concept http://linked.opendata.cz/ontology/domain/vavai/Vysledek
Description	These results demonstrate that activation of astroglial ionotropic NMDA and P2X1/5 receptors increases intracellular free calcium in cortical astrocytes when stimulated by endogenous agonists and synaptic release of neurotransmitters. These data suggest contribution of NMDA and P2X1/5 receptors to astroglial calcium signalling, which may provide a specific mechanism for fast neuronal-glial signalling at the synaptic level. These results demonstrate that activation of astroglial ionotropic NMDA and P2X1/5 receptors increases intracellular free calcium in cortical astrocytes when stimulated by endogenous agonists and synaptic release of neurotransmitters. These data suggest contribution of NMDA and P2X1/5 receptors to astroglial calcium signalling, which may provide a specific mechanism for fast neuronal-glial signalling at the synaptic level. (en)
Title	Ionotropic NMDA and P2X1/5 receptors mediate synaptically induced Ca2+ signalling in cortical astrocytes Ionotropic NMDA and P2X1/5 receptors mediate synaptically induced Ca2+ signalling in cortical astrocytes (en)
skos:prefLabel	Ionotropic NMDA and P2X1/5 receptors mediate synaptically induced Ca2+ signalling in cortical astrocytes Ionotropic NMDA and P2X1/5 receptors mediate synaptically induced Ca2+ signalling in cortical astrocytes (en)
skos:notation	RIV/68378041:_____/10:00350431!RIV11-GA0-68378041
http://linked.open...avai/riv/aktivita	P Z
http://linked.open...avai/riv/aktivity	P(GA305/08/1384), Z(AV0Z50390703)
http://linked.open...iv/cisloPeriodika	4
http://linked.open...vai/riv/dodaniDat	2011
http://linked.open...aciTvurceVysledku	Verkhratsky, Alexei
http://linked.open.../riv/druhVysledku	J - Článek v odborném periodiku
http://linked.open...iv/duvernostUdaju	S - Úplné a pravdivé údaje nepodléhající ochraně podle zvláštních právních předpisů
http://linked.open...titaPredkladatele	Ústav experimentální medicíny AV ČR, v. v. i.
http://linked.open...dnocenehoVysledku	264906
http://linked.open...ai/riv/idVysledku	RIV/68378041:_____/10:00350431
http://linked.open...riv/jazykVysledku	eng - angličtina
http://linked.open.../riv/klicovaSlova	Astroglia; Ca2+ signalling; NMDA receptors (en)
http://linked.open.../riv/klicoveSlovo	NMDA receptors Ca2+ signalling Astroglia
http://linked.open...odStatuVydavatele	DE - Spolková republika Německo
http://linked.open...ontrolniKodProRIV	[B8D25D2D078D]
http://linked.open...i/riv/nazevZdroje	Cell Calcium
http://linked.open...in/vavai/riv/obor	FH
http://linked.open...ichTvurcuVysledku	1 (xsd:int)
http://linked.open...cetTvurcuVysledku	4 (xsd:int)
http://linked.open...vavai/riv/projekt	Age-related changes in the structure and function of astrocytes
http://linked.open...UplatneniVysledku	2010
http://linked.open...v/svazekPeriodika	48
http://linked.open...iv/tvurceVysledku	Lalo, U. Palygin, O. Pankratov, Y. Verkhratsky, Alexei
http://linked.open...ain/vavai/riv/wos	000284659100006
http://linked.open...n/vavai/riv/zamer	New biotechnologies, nanomaterials and stem cells for use in regenerative medicine
issn	0143-4160
number of pages	7 (xsd:int)
is http://linked.open...avai/riv/vysledek of	Ionotropic NMDA and P2X1/5 receptors mediate synaptically induced Ca2+ signalling in cortical astrocytes Ionotropic NMDA and P2X1/5 receptors mediate synaptically induced Ca2+ signalling in cortical astrocytes Ionotropic NMDA and P2X1/5 receptors mediate synaptically induced Ca2+ signalling in cortical astrocytes

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