About: Ontogenetic Development of GABA(B)-Receptor Signaling Cascade in Plasma Membranes Isolated From Rat Brain Cortex; the Number of GABA(B)-Receptors Is High Already Shortly After the Birth     Goto   Sponge   Distinct   Permalink

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  • Our data indicate the significant intrinsic efficacy of GABAB-receptors in rat brain cortex already at birth (PD1, PD2). The potency of G-protein response to baclofen (characterized by EC50 values) was also high at birth but unchanged by further postnatal development. The highest plasma membrane density of GABAB-R was measured in 1-day old animals
  • Our data indicate the significant intrinsic efficacy of GABAB-receptors in rat brain cortex already at birth (PD1, PD2). The potency of G-protein response to baclofen (characterized by EC50 values) was also high at birth but unchanged by further postnatal development. The highest plasma membrane density of GABAB-R was measured in 1-day old animals (en)
Title
  • Ontogenetic Development of GABA(B)-Receptor Signaling Cascade in Plasma Membranes Isolated From Rat Brain Cortex; the Number of GABA(B)-Receptors Is High Already Shortly After the Birth
  • Ontogenetic Development of GABA(B)-Receptor Signaling Cascade in Plasma Membranes Isolated From Rat Brain Cortex; the Number of GABA(B)-Receptors Is High Already Shortly After the Birth (en)
skos:prefLabel
  • Ontogenetic Development of GABA(B)-Receptor Signaling Cascade in Plasma Membranes Isolated From Rat Brain Cortex; the Number of GABA(B)-Receptors Is High Already Shortly After the Birth
  • Ontogenetic Development of GABA(B)-Receptor Signaling Cascade in Plasma Membranes Isolated From Rat Brain Cortex; the Number of GABA(B)-Receptors Is High Already Shortly After the Birth (en)
skos:notation
  • RIV/67985823:_____/12:00388553!RIV13-GA0-67985823
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  • I, P(GAP207/12/0919), P(GBP304/12/G069), Z(AV0Z50110509)
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  • 6
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  • 156587
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  • RIV/67985823:_____/12:00388553
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  • postnatal development; GABAB-receptors; G-protein coupling/activation; baclofen; SKF97541 (en)
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  • CZ - Česká republika
http://linked.open...ontrolniKodProRIV
  • [AA9938EEBFBA]
http://linked.open...i/riv/nazevZdroje
  • Physiological Research
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  • 61
http://linked.open...iv/tvurceVysledku
  • Svoboda, Petr
  • Kagan, Dmytro
  • Dlouhá, Kateřina
  • Roubalová, Lenka
http://linked.open...ain/vavai/riv/wos
  • 000314138600008
http://linked.open...n/vavai/riv/zamer
issn
  • 0862-8408
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