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Description
| - Carbon fibre-reinforced carbon composites (CFRC), i.e. materials promising for hard tissue surgery, were coated by a fullerene layer in order to strengthen the material surface and create its nanostructure pattern which is known to be attractive for colonization with bone cells. Both human osteoblast-like MG 63 cells and rat vascular smooth muscle cells in 1- and 2-day-old cultures adhered to these surfaces in lower numbers in comparison with the control uncoated material and tissue culture polystyrene. On the other hand, the spreading of MG 63 cells was comparable to that observed on the control surfaces, and these cells also assembled dot-like vinculin-containing focal adhesion plaques and relatively rich fine filamentous beta-actin cytoskeleton. We suppose that the cell adhesion may be enhanced by derivatization of fullerenes with specific chemical functional groups or peptidic ligands for cell adhesion receptors
- Carbon fibre-reinforced carbon composites (CFRC), i.e. materials promising for hard tissue surgery, were coated by a fullerene layer in order to strengthen the material surface and create its nanostructure pattern which is known to be attractive for colonization with bone cells. Both human osteoblast-like MG 63 cells and rat vascular smooth muscle cells in 1- and 2-day-old cultures adhered to these surfaces in lower numbers in comparison with the control uncoated material and tissue culture polystyrene. On the other hand, the spreading of MG 63 cells was comparable to that observed on the control surfaces, and these cells also assembled dot-like vinculin-containing focal adhesion plaques and relatively rich fine filamentous beta-actin cytoskeleton. We suppose that the cell adhesion may be enhanced by derivatization of fullerenes with specific chemical functional groups or peptidic ligands for cell adhesion receptors (en)
- Kompozity s uhlíkovou matricí vyztuženou uhlíkovými vlákny (CFRC), nadějné materiály pro chirurgii tvrdých tkání, byly pokryty vrstvou fullerenů, a to jednak pro možné zpevnění povrchu materiálu, jednak pro vytvoření nanostruktury na tomto povrchu, která je známa svou atraktivitou pro kolonizaci kostními buňkami. Za 1 a 2 dny po nasazení adherovaly lidské kostní buňky linie MG 63 i cévní hladké svalové buňky aorty potkana k materiálu v nižším počtu ve srovnání s nepokrytými CFRC a polystyrénovou kultivační miskou. Na druhé straně velikost adhesní plochy byla u kostních buněk srovnatelná s hodnotou naměřenou na kontrolních površích, a tyto buňky rovněž vytvářely tečkovité vinkulinové fokální adhese a relativně dobře vyvinutý beta-aktiniový cytoskelet. Předpokládáme, že adhese buněk na fullerenech by mohla být dále zvýšena funkcionalizací fullerenů specifickými chemickými skupinami i oligopeptidickými ligandy pro adhesní receptory buněk (cs)
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Title
| - Adhesion of bone and vascular cells on carbon fibre-reinforced carbon composites coated with a fullerene layer
- Adhesion of bone and vascular cells on carbon fibre-reinforced carbon composites coated with a fullerene layer (en)
- Adhese kostních a cévních buněk na uhlíkové kompozity pokryté vrstvou fullerenů (cs)
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skos:prefLabel
| - Adhesion of bone and vascular cells on carbon fibre-reinforced carbon composites coated with a fullerene layer
- Adhesion of bone and vascular cells on carbon fibre-reinforced carbon composites coated with a fullerene layer (en)
- Adhese kostních a cévních buněk na uhlíkové kompozity pokryté vrstvou fullerenů (cs)
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skos:notation
| - RIV/67985823:_____/05:00025186!RIV06-AV0-67985823
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http://linked.open.../vavai/riv/strany
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http://linked.open...avai/riv/aktivita
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http://linked.open...avai/riv/aktivity
| - P(1P05OC012), P(OC 527.130), Z(AV0Z50110509)
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http://linked.open...iv/cisloPeriodika
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http://linked.open...vai/riv/dodaniDat
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http://linked.open...aciTvurceVysledku
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http://linked.open.../riv/druhVysledku
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http://linked.open...iv/duvernostUdaju
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http://linked.open...titaPredkladatele
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http://linked.open...dnocenehoVysledku
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http://linked.open...ai/riv/idVysledku
| - RIV/67985823:_____/05:00025186
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http://linked.open...riv/jazykVysledku
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http://linked.open.../riv/klicovaSlova
| - carbon fibre-reinforced carbon composites (CFRC); MG 63 cells; fullerenes C(60) (en)
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http://linked.open.../riv/klicoveSlovo
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http://linked.open...odStatuVydavatele
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http://linked.open...ontrolniKodProRIV
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http://linked.open...i/riv/nazevZdroje
| - Engineering of Biomaterials
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http://linked.open...in/vavai/riv/obor
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http://linked.open...ichTvurcuVysledku
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http://linked.open...cetTvurcuVysledku
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http://linked.open...vavai/riv/projekt
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http://linked.open...UplatneniVysledku
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http://linked.open...v/svazekPeriodika
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http://linked.open...iv/tvurceVysledku
| - Bačáková, Lucie
- Vacík, Jiří
- Grausová, Lubica
- Jungová, I.
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http://linked.open...n/vavai/riv/zamer
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issn
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number of pages
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is http://linked.open...avai/riv/vysledek
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