About: Visfatin is secreted into the breast milk and is correlated with weight changes of the infant after the birth

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An Entity of Type : http://linked.opendata.cz/ontology/domain/vavai/Vysledek, within Data Space : linked.opendata.cz associated with source document(s)

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rdf:type	skos:Concept http://linked.opendata.cz/ontology/domain/vavai/Vysledek
Description	Visfatin is a recently identified adipokine with numerous metabolic and immunoregulatory properties that has been implicated in the regulation of the white adipose tissue (WAT) and significant changes in visfatin levels were reported during pregnancy. The aim of the study was to investigate dynamics of visfatin levels in maternal serum and human breast milk during a 180-d period after the delivery. Breast milk and venous blood samples were obtained from 24 healthy lactating women with uncomplicated, physiological pregnancy and appropriate- for-gestational age neonates and serum–milk sample duos were collected at the time of birth, at the 1–3, 12–14, 28–30, 88–90 and 178–180 postpartum. Our study demonstrates that (1) visfatin is abundantly secreted into breast milk in humans, reaching approx. 100x higher concentrations compared to maternal serum; (2) visfatin concentrations in maternal serum show significant variations after the delivery and (3) visfatin concentration in colostrum could be used for prediction of the subsequent weight development (less/more severe weight loss during first 3 days after the birth) of the infant. Our data suggest that visfatin could play an important role in regulation of adiposity of the infatn after the birth. Visfatin is a recently identified adipokine with numerous metabolic and immunoregulatory properties that has been implicated in the regulation of the white adipose tissue (WAT) and significant changes in visfatin levels were reported during pregnancy. The aim of the study was to investigate dynamics of visfatin levels in maternal serum and human breast milk during a 180-d period after the delivery. Breast milk and venous blood samples were obtained from 24 healthy lactating women with uncomplicated, physiological pregnancy and appropriate- for-gestational age neonates and serum–milk sample duos were collected at the time of birth, at the 1–3, 12–14, 28–30, 88–90 and 178–180 postpartum. Our study demonstrates that (1) visfatin is abundantly secreted into breast milk in humans, reaching approx. 100x higher concentrations compared to maternal serum; (2) visfatin concentrations in maternal serum show significant variations after the delivery and (3) visfatin concentration in colostrum could be used for prediction of the subsequent weight development (less/more severe weight loss during first 3 days after the birth) of the infant. Our data suggest that visfatin could play an important role in regulation of adiposity of the infatn after the birth. (en)
Title	Visfatin is secreted into the breast milk and is correlated with weight changes of the infant after the birth Visfatin is secreted into the breast milk and is correlated with weight changes of the infant after the birth (en)
skos:prefLabel	Visfatin is secreted into the breast milk and is correlated with weight changes of the infant after the birth Visfatin is secreted into the breast milk and is correlated with weight changes of the infant after the birth (en)
skos:notation	RIV/65269705:_____/12:#0001630!RIV13-MZ0-65269705
http://linked.open...avai/predkladatel	Fakultní nemocnice Brno
http://linked.open...avai/riv/aktivita	N V
http://linked.open...avai/riv/aktivity	N, V
http://linked.open...iv/cisloPeriodika	3
http://linked.open...vai/riv/dodaniDat	2013
http://linked.open...aciTvurceVysledku	Dostálová, Zuzana
http://linked.open.../riv/druhVysledku	J - Článek v odborném periodiku
http://linked.open...iv/duvernostUdaju	S - Úplné a pravdivé údaje nepodléhající ochraně podle zvláštních právních předpisů
http://linked.open...titaPredkladatele	Fakultní nemocnice Brno / (nerozlišená součást)
http://linked.open...dnocenehoVysledku	177551
http://linked.open...ai/riv/idVysledku	RIV/65269705:_____/12:#0001630
http://linked.open...riv/jazykVysledku	eng - angličtina
http://linked.open.../riv/klicovaSlova	breast milk (en)
http://linked.open.../riv/klicoveSlovo	breast milk
http://linked.open...odStatuVydavatele	IE - Irsko
http://linked.open...ontrolniKodProRIV	[77D3850FA268]
http://linked.open...i/riv/nazevZdroje	Diabetes Research and Clinical Practice
http://linked.open...in/vavai/riv/obor	FK
http://linked.open...ichTvurcuVysledku	1 (xsd:int)
http://linked.open...cetTvurcuVysledku	7 (xsd:int)
http://linked.open...UplatneniVysledku	2012
http://linked.open...v/svazekPeriodika	96
http://linked.open...iv/tvurceVysledku	Bienertová-Vašků, Julie Dostálová Hodická, Zuzana
http://linked.open...ain/vavai/riv/wos	000305281100024
issn	0168-8227
number of pages	7 (xsd:int)
http://bibframe.org/vocab/doi	10.1016/j.diabres.2011.06.009
is http://linked.open...avai/riv/vysledek of	Visfatin is secreted into the breast milk and is correlated with weight changes of the infant after the birth

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