About: Changes in heart rate after application of newly developed ultrashort acting beta-adrenergic blockers.     Goto   Sponge   Distinct   Permalink

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  • The influence of the newly developed ultrashort acting beta-adrenergic blockers on the heart rate was measured on laboratory male Wistar rats with normal blood pressure. Three tested compounds were injected intravenously under general anaesthesia into the animals. At specific time intervals, the heart rate in all animals was measured from a record of their ECG. These results were converted into the percentages of perturbations of the heart rate. All evaluated compounds have shown a significant verifiable short-term bradycardic effect on the heart rate. The most significant reduction was observed in the first few minutes after i.v. administration.
  • The influence of the newly developed ultrashort acting beta-adrenergic blockers on the heart rate was measured on laboratory male Wistar rats with normal blood pressure. Three tested compounds were injected intravenously under general anaesthesia into the animals. At specific time intervals, the heart rate in all animals was measured from a record of their ECG. These results were converted into the percentages of perturbations of the heart rate. All evaluated compounds have shown a significant verifiable short-term bradycardic effect on the heart rate. The most significant reduction was observed in the first few minutes after i.v. administration. (en)
Title
  • Changes in heart rate after application of newly developed ultrashort acting beta-adrenergic blockers.
  • Changes in heart rate after application of newly developed ultrashort acting beta-adrenergic blockers. (en)
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  • Changes in heart rate after application of newly developed ultrashort acting beta-adrenergic blockers.
  • Changes in heart rate after application of newly developed ultrashort acting beta-adrenergic blockers. (en)
skos:notation
  • RIV/62157124:16370/03:00000015!RIV/2004/MSM/163704/N
http://linked.open.../vavai/riv/strany
  • 841-842
http://linked.open...avai/riv/aktivita
http://linked.open...avai/riv/aktivity
  • Z(MSM 161700002), Z(MSM 163700003)
http://linked.open...iv/cisloPeriodika
  • 4
http://linked.open...vai/riv/dodaniDat
http://linked.open...aciTvurceVysledku
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http://linked.open...iv/duvernostUdaju
http://linked.open...titaPredkladatele
http://linked.open...dnocenehoVysledku
  • 600833
http://linked.open...ai/riv/idVysledku
  • RIV/62157124:16370/03:00000015
http://linked.open...riv/jazykVysledku
http://linked.open.../riv/klicovaSlova
  • Laboratory rat, ultrashort acting beta-blockers, heart rate, ECG changes (en)
http://linked.open.../riv/klicoveSlovo
http://linked.open...odStatuVydavatele
  • DE - Spolková republika Německo
http://linked.open...ontrolniKodProRIV
  • [CABB2F1433DA]
http://linked.open...i/riv/nazevZdroje
  • Pharmazie
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http://linked.open...ichTvurcuVysledku
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http://linked.open...UplatneniVysledku
http://linked.open...v/svazekPeriodika
  • 58
http://linked.open...iv/tvurceVysledku
  • Mokrý, Petr
  • Bartošová, Ladislava
  • Kotolová, Hana
  • Brunclík, Vít
  • Frydrych, Marek
http://linked.open...n/vavai/riv/zamer
issn
  • 0031-7144
number of pages
http://localhost/t...ganizacniJednotka
  • 16370
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