About: Observation of changes in heart rate after newly developed ultrashort acting beta-adrenergic blockers were applied

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rdf:type	skos:Concept http://linked.opendata.cz/ontology/domain/vavai/Vysledek
Description	The influence of the newly developed ultrashort acting beta-adrenergic blockers on the heart rate was measured on laboratory male Wistar rats with normal blood pressure. Three tested compounds were injected intravenously under general anaesthesia into the animals. At specific time intervals, the heart rate in all animals was measured from a record of their ECG. These results were converted into the percentages of perturbations of the heart rate. All evaluated compounds have shown a significant verifiable short-term bradycardic effect on the heart rate. The most significant reduction was observed in the first few minutes after i.v. administration. The influence of the newly developed ultrashort acting beta-adrenergic blockers on the heart rate was measured on laboratory male Wistar rats with normal blood pressure. Three tested compounds were injected intravenously under general anaesthesia into the animals. At specific time intervals, the heart rate in all animals was measured from a record of their ECG. These results were converted into the percentages of perturbations of the heart rate. All evaluated compounds have shown a significant verifiable short-term bradycardic effect on the heart rate. The most significant reduction was observed in the first few minutes after i.v. administration. (en)
Title	Observation of changes in heart rate after newly developed ultrashort acting beta-adrenergic blockers were applied Observation of changes in heart rate after newly developed ultrashort acting beta-adrenergic blockers were applied (en)
skos:prefLabel	Observation of changes in heart rate after newly developed ultrashort acting beta-adrenergic blockers were applied Observation of changes in heart rate after newly developed ultrashort acting beta-adrenergic blockers were applied (en)
skos:notation	RIV/62157124:16370/02:00000657!RIV/2003/MSM/163703/N
http://linked.open.../vavai/riv/strany	303-304
http://linked.open...avai/riv/aktivita	Z
http://linked.open...avai/riv/aktivity	Z(MSM 163700003)
http://linked.open...iv/cisloPeriodika	9
http://linked.open...vai/riv/dodaniDat	2003
http://linked.open...aciTvurceVysledku	Mokrý, Petr Bartošíková, Lenka Nečas, Jiří Brunclík, Vít Bartošová, L.
http://linked.open.../riv/druhVysledku	J - Článek v odborném periodiku
http://linked.open...iv/duvernostUdaju	S - Úplné a pravdivé údaje nepodléhající ochraně podle zvláštních právních předpisů
http://linked.open...titaPredkladatele	Veterinární a farmaceutická univerzita Brno / Farmaceutická fakulta
http://linked.open...dnocenehoVysledku	656492
http://linked.open...ai/riv/idVysledku	RIV/62157124:16370/02:00000657
http://linked.open...riv/jazykVysledku	eng - angličtina
http://linked.open.../riv/klicovaSlova	Ultrashort acting beta-blockers, heart rate, ECG changes, ion channels (en)
http://linked.open.../riv/klicoveSlovo	ion channels heart rate ECG changes Ultrashort acting beta-blockers
http://linked.open...odStatuVydavatele	CZ - Česká republika
http://linked.open...ontrolniKodProRIV	[E372481256AD]
http://linked.open...i/riv/nazevZdroje	Bratislavske Lekarske Listy
http://linked.open...in/vavai/riv/obor	FR
http://linked.open...ichTvurcuVysledku	5 (xsd:int)
http://linked.open...cetTvurcuVysledku	7 (xsd:int)
http://linked.open...ocetUcastnikuAkce	0 (xsd:int)
http://linked.open...nichUcastnikuAkce	0 (xsd:int)
http://linked.open...UplatneniVysledku	2002
http://linked.open...v/svazekPeriodika	103
http://linked.open...iv/tvurceVysledku	Mokrý, Petr Nečas, Jiří Bartošová, Ladislava Bartošíková, Lenka Brunclík, Vít Frydrych, Marek Florian, Tomáš
http://linked.open...n/vavai/riv/zamer	http://linked.opendata.cz/resource/domain/vavai/zamer/MSM%20163700003
issn	0006-9248
number of pages	1 (xsd:int)
http://localhost/t...ganizacniJednotka	16370

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