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Description
| - Kardioprotektivní efekt ethylacetátové frakce Prunella vulgaris (PVEF) a kyselin rozmarýnové (RA) vůči toxickému působení doxorubicinu byl studován na izolovaných potkaních kardiomyocytech. Cytoprotektivní účinek PVEF a RA byl koncentračně závislý v rozsahu 0.005 - 0.05 mg/ml, účinek PVEF koreloval s obsahem RA. Dexrazoxan (DE), který byl použit jako pozitivní kontrola, byl méně účinný než PVEF nebo RA. (cs)
- The cardioprotective effect of Prunella vulgaris ethylacetate fraction (PVEF) and its constituent rosmarinic acid (RA) was evaluated on isolated rat cardiomyocytes subjected to doxorubicin-induced oxidative stress. The cytoprotectivities of PVEF and RA were concentration-dependent in the range of 0.005 to 0.05 mg/ml and the effect of PVEF correlated with the RA content. Dexrazoxan (DE), used as positive control, was less effective than PVEF or RA.
- The cardioprotective effect of Prunella vulgaris ethylacetate fraction (PVEF) and its constituent rosmarinic acid (RA) was evaluated on isolated rat cardiomyocytes subjected to doxorubicin-induced oxidative stress. The cytoprotectivities of PVEF and RA were concentration-dependent in the range of 0.005 to 0.05 mg/ml and the effect of PVEF correlated with the RA content. Dexrazoxan (DE), used as positive control, was less effective than PVEF or RA. (en)
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Title
| - Cytoprotectivity of Prunella vulgaris on doxorubicin-treated rat cardiomyocytes
- Cytoprotectivity of Prunella vulgaris on doxorubicin-treated rat cardiomyocytes (en)
- Cytoprotektivita Prunelly vulgaris na potkaních kardiomyocytech inkubovaných doxorubicinem (cs)
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skos:prefLabel
| - Cytoprotectivity of Prunella vulgaris on doxorubicin-treated rat cardiomyocytes
- Cytoprotectivity of Prunella vulgaris on doxorubicin-treated rat cardiomyocytes (en)
- Cytoprotektivita Prunelly vulgaris na potkaních kardiomyocytech inkubovaných doxorubicinem (cs)
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skos:notation
| - RIV/61989592:15110/05:00001982!RIV06-MSM-15110___
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http://linked.open.../vavai/riv/strany
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http://linked.open...avai/riv/aktivita
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http://linked.open...avai/riv/aktivity
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http://linked.open...iv/cisloPeriodika
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http://linked.open...vai/riv/dodaniDat
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http://linked.open...aciTvurceVysledku
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http://linked.open.../riv/druhVysledku
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http://linked.open...iv/duvernostUdaju
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http://linked.open...titaPredkladatele
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http://linked.open...dnocenehoVysledku
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http://linked.open...ai/riv/idVysledku
| - RIV/61989592:15110/05:00001982
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http://linked.open...riv/jazykVysledku
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http://linked.open.../riv/klicovaSlova
| - Prunella vulgaris; rosmarinic acid; rardiomyocyte; roxorubicin; chemoprotection (en)
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http://linked.open.../riv/klicoveSlovo
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http://linked.open...odStatuVydavatele
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http://linked.open...ontrolniKodProRIV
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http://linked.open...i/riv/nazevZdroje
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http://linked.open...in/vavai/riv/obor
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http://linked.open...ichTvurcuVysledku
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http://linked.open...cetTvurcuVysledku
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http://linked.open...UplatneniVysledku
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http://linked.open...v/svazekPeriodika
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http://linked.open...iv/tvurceVysledku
| - Šimánek, Vilím
- Psotová, Jitka
- Chlopčíková, Šárka
- Miketová, Petra
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http://linked.open...n/vavai/riv/zamer
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issn
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number of pages
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http://localhost/t...ganizacniJednotka
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