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Description
| - In Drosophila, the compound eye photoreceptors and the H-B eyelet, a specialized photoreceptive structure located between the retina and the optic lobes, contain Rhodopsin photopigments, which activate the canonical invertebrate phototransduction cascade after being excited by light. We show that 2 of the photopigments present in these photoreceptors, Rhodopsin 5 (Rh5) and Rhodopsin 6 (Rh6), contribute to light synchronization in a mutant (norpAP41) that disrupts canonical phototransduction due to the absence of Phospholipase C-β(PLC-β). We reveal that norpAP41 is a true loss-of-function allele, resulting in a truncated PLC-βprotein that lacks the catalytic domain. Light reception mediated by Rh5 and Rh6 must therefore utilize either a different (nonretinal) PLC-βenzyme or alternative signaling mechanisms, at least in terms of clockrelevant photoreception.
- In Drosophila, the compound eye photoreceptors and the H-B eyelet, a specialized photoreceptive structure located between the retina and the optic lobes, contain Rhodopsin photopigments, which activate the canonical invertebrate phototransduction cascade after being excited by light. We show that 2 of the photopigments present in these photoreceptors, Rhodopsin 5 (Rh5) and Rhodopsin 6 (Rh6), contribute to light synchronization in a mutant (norpAP41) that disrupts canonical phototransduction due to the absence of Phospholipase C-β(PLC-β). We reveal that norpAP41 is a true loss-of-function allele, resulting in a truncated PLC-βprotein that lacks the catalytic domain. Light reception mediated by Rh5 and Rh6 must therefore utilize either a different (nonretinal) PLC-βenzyme or alternative signaling mechanisms, at least in terms of clockrelevant photoreception. (en)
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Title
| - Rhodpsin 5- and Rhodopsin 6-mediated clock synchronization in Drosophila melanogaster in independent of retinal phospholipase C-beta signaling
- Rhodpsin 5- and Rhodopsin 6-mediated clock synchronization in Drosophila melanogaster in independent of retinal phospholipase C-beta signaling (en)
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skos:prefLabel
| - Rhodpsin 5- and Rhodopsin 6-mediated clock synchronization in Drosophila melanogaster in independent of retinal phospholipase C-beta signaling
- Rhodpsin 5- and Rhodopsin 6-mediated clock synchronization in Drosophila melanogaster in independent of retinal phospholipase C-beta signaling (en)
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skos:notation
| - RIV/60077344:_____/12:00390649!RIV13-AV0-60077344
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http://linked.open...avai/predkladatel
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http://linked.open...avai/riv/aktivita
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http://linked.open...avai/riv/aktivity
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http://linked.open...iv/cisloPeriodika
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http://linked.open...vai/riv/dodaniDat
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http://linked.open...aciTvurceVysledku
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http://linked.open.../riv/druhVysledku
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http://linked.open...iv/duvernostUdaju
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http://linked.open...titaPredkladatele
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http://linked.open...dnocenehoVysledku
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http://linked.open...ai/riv/idVysledku
| - RIV/60077344:_____/12:00390649
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http://linked.open...riv/jazykVysledku
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http://linked.open.../riv/klicovaSlova
| - Rhodopsin 5; Rhodopsin 6; phospholipase (en)
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http://linked.open.../riv/klicoveSlovo
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http://linked.open...odStatuVydavatele
| - US - Spojené státy americké
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http://linked.open...ontrolniKodProRIV
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http://linked.open...i/riv/nazevZdroje
| - Journal of Biological Rhythms
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http://linked.open...in/vavai/riv/obor
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http://linked.open...ichTvurcuVysledku
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http://linked.open...cetTvurcuVysledku
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http://linked.open...UplatneniVysledku
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http://linked.open...v/svazekPeriodika
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http://linked.open...iv/tvurceVysledku
| - Sehadová, Hana
- Stanewsky, R.
- Britt, S. G.
- Chou, W.-H.
- Gentile, C.
- Szabo, G.
- Szular, J.
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http://linked.open...ain/vavai/riv/wos
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issn
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number of pages
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http://bibframe.org/vocab/doi
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is http://linked.open...avai/riv/vysledek
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