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Description
| - The aim of this study was to determine if there is any difference in PML protein expression between tumors with stable microsatellites (MSS) and those with high-frequency microsatellite instability (MSI-H), if PML protein expression might be a prognostic factor and if MSI-H tumors more frequently use alternative lengthening of telomeres measured by the presence of ALT-associated PML bodies. The PML protein was downregulated in approximately 20% of tumors; there was no difference between MSS and MSI-H tumors. PML protein expression does not seem to be a prognostic factor.
- The aim of this study was to determine if there is any difference in PML protein expression between tumors with stable microsatellites (MSS) and those with high-frequency microsatellite instability (MSI-H), if PML protein expression might be a prognostic factor and if MSI-H tumors more frequently use alternative lengthening of telomeres measured by the presence of ALT-associated PML bodies. The PML protein was downregulated in approximately 20% of tumors; there was no difference between MSS and MSI-H tumors. PML protein expression does not seem to be a prognostic factor. (en)
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Title
| - PML and TRF2 protein expression in hereditary and sporadic colon cancer
- PML and TRF2 protein expression in hereditary and sporadic colon cancer (en)
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skos:prefLabel
| - PML and TRF2 protein expression in hereditary and sporadic colon cancer
- PML and TRF2 protein expression in hereditary and sporadic colon cancer (en)
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skos:notation
| - RIV/00843989:_____/07:00014879!RIV12-MZ0-00843989
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http://linked.open...avai/riv/aktivita
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http://linked.open...avai/riv/aktivity
| - P(NR9092), S, V, Z(MSM6198959216)
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http://linked.open...iv/cisloPeriodika
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http://linked.open...vai/riv/dodaniDat
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http://linked.open...aciTvurceVysledku
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http://linked.open.../riv/druhVysledku
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http://linked.open...iv/duvernostUdaju
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http://linked.open...titaPredkladatele
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http://linked.open...dnocenehoVysledku
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http://linked.open...ai/riv/idVysledku
| - RIV/00843989:_____/07:00014879
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http://linked.open...riv/jazykVysledku
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http://linked.open.../riv/klicovaSlova
| - PML; TRF2; alternative lengthening of telomeres; hMLH1-gene; hMSH2-gene; microsatellite instability (en)
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http://linked.open.../riv/klicoveSlovo
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http://linked.open...odStatuVydavatele
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http://linked.open...ontrolniKodProRIV
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http://linked.open...i/riv/nazevZdroje
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http://linked.open...in/vavai/riv/obor
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http://linked.open...ichTvurcuVysledku
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http://linked.open...cetTvurcuVysledku
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http://linked.open...vavai/riv/projekt
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http://linked.open...UplatneniVysledku
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http://linked.open...v/svazekPeriodika
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http://linked.open...iv/tvurceVysledku
| - Bouchal, J.
- Zapletalová, J.
- Foretová, L.
- Kolář, Z.
- Posolda, Tomáš
- Čuřík, Romuald
- Plevová, P.
- Navrátilová, M.
- Křepelová, A.
- Papežová, M.
- Fiurášková, M.
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http://linked.open...ain/vavai/riv/wos
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http://linked.open...n/vavai/riv/zamer
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issn
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number of pages
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