About: Synthesis, characterization and antibacterial activity of new fluorescent chitosan derivatives     Goto   Sponge   Distinct   Permalink

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  • The present work aims to the development of innovative new derivatives of chitosan that can be used for medical applications. This innovation is based on the synthesis and characterization of chitosan-g-aminoanthracene derivatives. Thus, N-(anthracen-9-yl)-4,6- dichloro-[1,3,5]-triazin-2-amine (AT) reacted with chitosan by the following steps: At first, cyanuric chloride reacted with 9-aminoanthracene to obtain N-(anthracen-9-yl)-4,6-dichloro- 40 [1,3,5]-triazin-2-amine (AT), then the AT reacted with chitosan to obtain (CH -g-AT). The final product of CH-g-AT was separated, purified and re-crystallized by dioxan. The structure of the prepared chitosan derivatives was confirmed by FTIR-ATR, solid-NMR, TGA, X-RD, and DSC. The new chitosan derivatives showed fluorescence spectra in liquid and in solid state as well. CH-g-AT showed also high antibacterial activity against gram-negative species (Escherichia coli).
  • The present work aims to the development of innovative new derivatives of chitosan that can be used for medical applications. This innovation is based on the synthesis and characterization of chitosan-g-aminoanthracene derivatives. Thus, N-(anthracen-9-yl)-4,6- dichloro-[1,3,5]-triazin-2-amine (AT) reacted with chitosan by the following steps: At first, cyanuric chloride reacted with 9-aminoanthracene to obtain N-(anthracen-9-yl)-4,6-dichloro- 40 [1,3,5]-triazin-2-amine (AT), then the AT reacted with chitosan to obtain (CH -g-AT). The final product of CH-g-AT was separated, purified and re-crystallized by dioxan. The structure of the prepared chitosan derivatives was confirmed by FTIR-ATR, solid-NMR, TGA, X-RD, and DSC. The new chitosan derivatives showed fluorescence spectra in liquid and in solid state as well. CH-g-AT showed also high antibacterial activity against gram-negative species (Escherichia coli). (en)
Title
  • Synthesis, characterization and antibacterial activity of new fluorescent chitosan derivatives
  • Synthesis, characterization and antibacterial activity of new fluorescent chitosan derivatives (en)
skos:prefLabel
  • Synthesis, characterization and antibacterial activity of new fluorescent chitosan derivatives
  • Synthesis, characterization and antibacterial activity of new fluorescent chitosan derivatives (en)
skos:notation
  • RIV/00216305:26620/14:PU107463!RIV15-MSM-26620___
http://linked.open...avai/riv/aktivita
http://linked.open...avai/riv/aktivity
  • I, P(ED1.1.00/02.0068), P(EE2.3.30.0005), S
http://linked.open...iv/cisloPeriodika
  • 1
http://linked.open...vai/riv/dodaniDat
http://linked.open...aciTvurceVysledku
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  • 49003
http://linked.open...ai/riv/idVysledku
  • RIV/00216305:26620/14:PU107463
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  • chitosan, antibacterial activity, fluorescent derivatives (en)
http://linked.open.../riv/klicoveSlovo
http://linked.open...odStatuVydavatele
  • NL - Nizozemsko
http://linked.open...ontrolniKodProRIV
  • [4B860F407761]
http://linked.open...i/riv/nazevZdroje
  • INTERNATIONAL JOURNAL OF BIOLOGICAL MACROMOLECULES
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http://linked.open...vavai/riv/projekt
http://linked.open...UplatneniVysledku
http://linked.open...v/svazekPeriodika
  • 65
http://linked.open...iv/tvurceVysledku
  • Burgert, Ladislav
  • Jančář, Josef
  • Vojtová, Lucy
  • Spotz, Zdeněk
  • Přichystalová, Hana
  • Almonasy, Numan
  • Abdel-Lattif, Abdel-Mohsan
  • Abdel-Rahman, Rasha M.
  • Fouda, Moustafa M.D.
  • Koběra, Libor
issn
  • 0141-8130
number of pages
http://localhost/t...ganizacniJednotka
  • 26620
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