About: Detection of cancer stem cell markers in sarcomas

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An Entity of Type : http://linked.opendata.cz/ontology/domain/vavai/Vysledek, within Data Space : linked.opendata.cz associated with source document(s)

Attributes	Values
rdf:type	skos:Concept http://linked.opendata.cz/ontology/domain/vavai/Vysledek
rdfs:seeAlso	http://www.linkos.cz/casopis-klinicka-onkologie/hledani-clanku/skupina/a/zobrazit/ids/4117/
Description	The identification of cancer stem cell markers represents one of the very relevant research topics because cancer stem cells play important roles in tumour initiation and progression, as well as during metastasis formation and in relapse of the disease. This article summarises recent knowledge on well-known and putative cancer stem cell markers in various types of bone and soft-tissue sarcomas. Special attention is paid to the detection of CD133, ABC transporters, nestin and aldehyde dehydrogenase that have been intensively studied both in tumour tissues and in sarcoma cell lines during the past few years. Finally, an overview is given of the possible CSC phenotypes provided by functional assays of tumourigenicity. The identification of cancer stem cell markers represents one of the very relevant research topics because cancer stem cells play important roles in tumour initiation and progression, as well as during metastasis formation and in relapse of the disease. This article summarises recent knowledge on well-known and putative cancer stem cell markers in various types of bone and soft-tissue sarcomas. Special attention is paid to the detection of CD133, ABC transporters, nestin and aldehyde dehydrogenase that have been intensively studied both in tumour tissues and in sarcoma cell lines during the past few years. Finally, an overview is given of the possible CSC phenotypes provided by functional assays of tumourigenicity. (en)
Title	Detection of cancer stem cell markers in sarcomas Detection of cancer stem cell markers in sarcomas (en)
skos:prefLabel	Detection of cancer stem cell markers in sarcomas Detection of cancer stem cell markers in sarcomas (en)
skos:notation	RIV/00216224:14310/12:00065657!RIV14-MZ0-14310___
http://linked.open...avai/predkladatel	Přírodovědecká fakulta
http://linked.open...avai/riv/aktivita	P
http://linked.open...avai/riv/aktivity	P(ED2.1.00/03.0101), P(NT13443)
http://linked.open...iv/cisloPeriodika	Suppl 2
http://linked.open...vai/riv/dodaniDat	2014
http://linked.open...aciTvurceVysledku	Veselská, Renata Neradil, Jakub Škoda, Jan
http://linked.open.../riv/druhVysledku	J - Článek v odborném periodiku
http://linked.open...iv/duvernostUdaju	S - Úplné a pravdivé údaje nepodléhající ochraně podle zvláštních právních předpisů
http://linked.open...titaPredkladatele	Masarykova univerzita / Přírodovědecká fakulta
http://linked.open...dnocenehoVysledku	130427
http://linked.open...ai/riv/idVysledku	RIV/00216224:14310/12:00065657
http://linked.open...riv/jazykVysledku	eng - angličtina
http://linked.open.../riv/klicovaSlova	cancer stem cells; osteosarcoma; rhabdomyosarcoma; CD133; ABC transporters; nestin; aldehyde dehydrogenase; tumourigenicity (en)
http://linked.open.../riv/klicoveSlovo	osteosarcoma ABC transporters nestin aldehyde dehydrogenase rhabdomyosarcoma tumourigenicity CD133 cancer stem cells
http://linked.open...odStatuVydavatele	CZ - Česká republika
http://linked.open...ontrolniKodProRIV	[89DB8B69E4DA]
http://linked.open...i/riv/nazevZdroje	Klinická onkologie
http://linked.open...in/vavai/riv/obor	EB
http://linked.open...ichTvurcuVysledku	3 (xsd:int)
http://linked.open...cetTvurcuVysledku	3 (xsd:int)
http://linked.open...vavai/riv/projekt	Regional Centre for Applied Molecular Oncology (RECAMO) Identification and characterization of cancer stem cells in pediatric sarcomas.
http://linked.open...UplatneniVysledku	2012
http://linked.open...v/svazekPeriodika	25
http://linked.open...iv/tvurceVysledku	Neradil, Jakub Veselská, Renata Škoda, Jan
issn	0862-495X
number of pages	5 (xsd:int)
http://localhost/t...ganizacniJednotka	14310

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