About: A new tool for distinguishing of different structural forms of lactoferrin

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An Entity of Type : http://linked.opendata.cz/ontology/domain/vavai/Vysledek, within Data Space : linked.opendata.cz associated with source document(s)

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rdf:type	skos:Concept http://linked.opendata.cz/ontology/domain/vavai/Vysledek
Description	Lactoferrin is considered a multifunctional or multi-tasking protein. It appears to play several biological roles, whereas its structure is very crucial. The aim of this work was to investigate basic electrochemical behaviour of lactoferrin by both stationary and flow electrochemical methods with respect to study of structural changes of the compound of interest. The behaviour of lactoferrin was studied by three various electrochemical methods (linear sweep, differential pulse and square wave voltammetry). Based on the results obtained, we utilized flow injection analysis with electrochemical detection for determination of lactoferrin. We found out that the most suitable FIA-ED conditions were as follows: working electrode potential of 900 mV, Britton-Robinson buffer (pH 4.5) as mobile phase, its flow rate 1 ml.min-1. The detection limit was about tens of ng per ml. Finally, we attempted to follow the changes of lactoferrin signal in the presence of chemical compounds or under the physical conditions Lactoferrin is considered a multifunctional or multi-tasking protein. It appears to play several biological roles, whereas its structure is very crucial. The aim of this work was to investigate basic electrochemical behaviour of lactoferrin by both stationary and flow electrochemical methods with respect to study of structural changes of the compound of interest. The behaviour of lactoferrin was studied by three various electrochemical methods (linear sweep, differential pulse and square wave voltammetry). Based on the results obtained, we utilized flow injection analysis with electrochemical detection for determination of lactoferrin. We found out that the most suitable FIA-ED conditions were as follows: working electrode potential of 900 mV, Britton-Robinson buffer (pH 4.5) as mobile phase, its flow rate 1 ml.min-1. The detection limit was about tens of ng per ml. Finally, we attempted to follow the changes of lactoferrin signal in the presence of chemical compounds or under the physical conditions (en) Nový nástroj pro rozdělení rozdílných strukturních forem laktoferinu (cs)
Title	A new tool for distinguishing of different structural forms of lactoferrin A new tool for distinguishing of different structural forms of lactoferrin (en) Nový nástroj pro rozdělení rozdílných strukturních forem laktoferinu (cs)
skos:prefLabel	A new tool for distinguishing of different structural forms of lactoferrin A new tool for distinguishing of different structural forms of lactoferrin (en) Nový nástroj pro rozdělení rozdílných strukturních forem laktoferinu (cs)
skos:notation	RIV/00216224:14310/07:00022110!RIV08-MSM-14310___
http://linked.open.../vavai/riv/strany	A635-A635
http://linked.open...avai/riv/aktivita	Z
http://linked.open...avai/riv/aktivity	Z(MSM0021622412)
http://linked.open...iv/cisloPeriodika	5
http://linked.open...vai/riv/dodaniDat	2008
http://linked.open...aciTvurceVysledku	Stejskal, Karel Trnková, Libuše Adam, Vojtěch Zehnálek, Josef Kizek, René Zítka, Ondřej
http://linked.open.../riv/druhVysledku	J - Článek v odborném periodiku
http://linked.open...iv/duvernostUdaju	S - Úplné a pravdivé údaje nepodléhající ochraně podle zvláštních právních předpisů
http://linked.open...titaPredkladatele	Masarykova univerzita / Přírodovědecká fakulta
http://linked.open...dnocenehoVysledku	408028
http://linked.open...ai/riv/idVysledku	RIV/00216224:14310/07:00022110
http://linked.open...riv/jazykVysledku	eng - angličtina
http://linked.open.../riv/klicovaSlova	distinguish; structural forms; lactoferrin; FIA-ED (en)
http://linked.open.../riv/klicoveSlovo	lactoferrin FIA-ED distinguish structural forms
http://linked.open...odStatuVydavatele	US - Spojené státy americké
http://linked.open...ontrolniKodProRIV	[FAA0D9F6029A]
http://linked.open...i/riv/nazevZdroje	Faseb J.
http://linked.open...in/vavai/riv/obor	CG
http://linked.open...ichTvurcuVysledku	6 (xsd:int)
http://linked.open...cetTvurcuVysledku	11 (xsd:int)
http://linked.open...UplatneniVysledku	2007
http://linked.open...v/svazekPeriodika	21
http://linked.open...iv/tvurceVysledku	Adam, Vojtěch Kizek, René Stejskal, Karel Trnková, Libuše Zehnálek, Josef Zítka, Ondřej Havel, L. Zeman, L. Kukačka, J. Průša, R. Horna, A.
http://linked.open...n/vavai/riv/zamer	Interactions among the chemicals, environment and biological systems and their consequences on the global, regional and local scales (INCHEMBIOL)
issn	0892-6638
number of pages	1 (xsd:int)
http://localhost/t...ganizacniJednotka	14310
is http://linked.open...avai/riv/vysledek of	A new tool for distinguishing of different structural forms of lactoferrin A new tool for distinguishing of different structural forms of lactoferrin A new tool for distinguishing of different structural forms of lactoferrin

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