About: Managed ventricular pacing compared with conventional dual-chamber pacing for elective replacement in chronically paced patients: Results of the Prefer for Elective Replacement Managed Ventricular Pacing randomized study     Goto   Sponge   Distinct   Permalink

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  • BACKGROUND Several studies have shown that unnecessary right ventricular pacing has detrimental effects. OBJECTIVE To evaluate whether minimization of ventricular pacing as compared with standard dual-chamber pacing (DDD) improves clinical outcomes in patients referred for pacemaker or implantable cardioverter-defibrillator (ICD) replacement. METHODS In an international single-blind, multicenter, randomized controlled trial, we compared DDD with managed ventricular pacing (MVP), a pacing mode developed to minimize ventricular pacing by promoting intrinsic atrioventricular conduction. We included patients referred for device replacement with >40% ventricular pacing, no cardiac resynchronization therapy upgrade indication, no permanent atrial fibrillation (AF), and no permanent complete atrioventricular block. Follow-up was for 2 years. The primary end point was cardiovascular hospitalization. The intention-to-treat analysis was performed by using Kaplan-Meier method and the log-rank test.
  • BACKGROUND Several studies have shown that unnecessary right ventricular pacing has detrimental effects. OBJECTIVE To evaluate whether minimization of ventricular pacing as compared with standard dual-chamber pacing (DDD) improves clinical outcomes in patients referred for pacemaker or implantable cardioverter-defibrillator (ICD) replacement. METHODS In an international single-blind, multicenter, randomized controlled trial, we compared DDD with managed ventricular pacing (MVP), a pacing mode developed to minimize ventricular pacing by promoting intrinsic atrioventricular conduction. We included patients referred for device replacement with >40% ventricular pacing, no cardiac resynchronization therapy upgrade indication, no permanent atrial fibrillation (AF), and no permanent complete atrioventricular block. Follow-up was for 2 years. The primary end point was cardiovascular hospitalization. The intention-to-treat analysis was performed by using Kaplan-Meier method and the log-rank test. (en)
Title
  • Managed ventricular pacing compared with conventional dual-chamber pacing for elective replacement in chronically paced patients: Results of the Prefer for Elective Replacement Managed Ventricular Pacing randomized study
  • Managed ventricular pacing compared with conventional dual-chamber pacing for elective replacement in chronically paced patients: Results of the Prefer for Elective Replacement Managed Ventricular Pacing randomized study (en)
skos:prefLabel
  • Managed ventricular pacing compared with conventional dual-chamber pacing for elective replacement in chronically paced patients: Results of the Prefer for Elective Replacement Managed Ventricular Pacing randomized study
  • Managed ventricular pacing compared with conventional dual-chamber pacing for elective replacement in chronically paced patients: Results of the Prefer for Elective Replacement Managed Ventricular Pacing randomized study (en)
skos:notation
  • RIV/00216224:14110/14:00079796!RIV15-MSM-14110___
http://linked.open...avai/riv/aktivita
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  • 27062
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  • RIV/00216224:14110/14:00079796
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  • Cardiac pacing; Managed ventricular pacing; Dual-chamber pacing; Randomized controlled trial; Outcomes (en)
http://linked.open.../riv/klicoveSlovo
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  • US - Spojené státy americké
http://linked.open...ontrolniKodProRIV
  • [D06E2BBE28E0]
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  • Heart Rhythm
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  • 11
http://linked.open...iv/tvurceVysledku
  • Kozák, Milan
  • Garutti, Claudio
  • Benezet, Juan M.
  • Botto, Giovanni L.
  • De Roy, Luc
  • Nielsen, Jens Cosedis
  • Piot, Olivier
  • Quaglione, Raffaele
  • Quesada, Aurelio
  • Ricci, Renato P.
  • Vaccari, Diego
  • Vainer, Lidwien
http://linked.open...ain/vavai/riv/wos
  • 000336395600013
issn
  • 1547-5271
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http://bibframe.org/vocab/doi
  • 10.1016/j.hrthm.2014.03.011
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  • 14110
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