About: Experimental assessment of a new type of vascular prostheses with Adiponectin (Adipograft Ra 7/350 ) on sheep     Goto   Sponge   Distinct   Permalink

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  • Despite medical advancements, the development of an ideal vascular prosthesis still poses a great challenge. In this study the researchers tried to test and verify the characteristics of a new type of vascular prosthesis, using adiponectin (Adipograft Ra 1vk 7/350) developed at the Knitting Research Institute, a.s. Brno. Two types of vascular prostheses (12 with adiponectin and 6 as a control without adiponectin) were implanted in nine healthy 4-year-old Merino sheep. The implantation site was the common carotid artery and the length of the implant was 10 cm. We applied the theory of the protected coagulum, whereby all sheep received antibiotics as a prophylactic measure. A Doppler U.S. was performed before fi nishing each operation, in order to verify the patency of the prostheses. Each animal was followed up during the whole study and the prostheses were extirpated on days 30 and 100 (1 and 3 months). It was observed that all prostheses coated with adiponectin showed patency after extirpation.
  • Despite medical advancements, the development of an ideal vascular prosthesis still poses a great challenge. In this study the researchers tried to test and verify the characteristics of a new type of vascular prosthesis, using adiponectin (Adipograft Ra 1vk 7/350) developed at the Knitting Research Institute, a.s. Brno. Two types of vascular prostheses (12 with adiponectin and 6 as a control without adiponectin) were implanted in nine healthy 4-year-old Merino sheep. The implantation site was the common carotid artery and the length of the implant was 10 cm. We applied the theory of the protected coagulum, whereby all sheep received antibiotics as a prophylactic measure. A Doppler U.S. was performed before fi nishing each operation, in order to verify the patency of the prostheses. Each animal was followed up during the whole study and the prostheses were extirpated on days 30 and 100 (1 and 3 months). It was observed that all prostheses coated with adiponectin showed patency after extirpation. (en)
Title
  • Experimental assessment of a new type of vascular prostheses with Adiponectin (Adipograft Ra 7/350 ) on sheep
  • Experimental assessment of a new type of vascular prostheses with Adiponectin (Adipograft Ra 7/350 ) on sheep (en)
skos:prefLabel
  • Experimental assessment of a new type of vascular prostheses with Adiponectin (Adipograft Ra 7/350 ) on sheep
  • Experimental assessment of a new type of vascular prostheses with Adiponectin (Adipograft Ra 7/350 ) on sheep (en)
skos:notation
  • RIV/00216224:14110/14:00077813!RIV15-MSM-14110___
http://linked.open...avai/riv/aktivita
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  • I
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  • 4
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http://linked.open...aciTvurceVysledku
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  • 15800
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  • RIV/00216224:14110/14:00077813
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  • adiponectin; experimental surgery; preclinical trial; vascular prosthesis. (en)
http://linked.open.../riv/klicoveSlovo
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  • RS - Srbská republika
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  • [CD4E972E4241]
http://linked.open...i/riv/nazevZdroje
  • Acta Veterinaria-Beograd
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http://linked.open...UplatneniVysledku
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  • 64
http://linked.open...iv/tvurceVysledku
  • Schwanhaeuser Wulff, Kräuff Rainer
  • Podlaha, Jiří
http://linked.open...ain/vavai/riv/wos
  • 000348509200003
issn
  • 0567-8315
number of pages
http://bibframe.org/vocab/doi
  • 10.2478/acve-2014-0040
http://localhost/t...ganizacniJednotka
  • 14110
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