About: Mismatch negativity-like potential (MMN-like) in the subthalamic nuclei in Parkinson’s disease patients

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rdf:type	skos:Concept http://linked.opendata.cz/ontology/domain/vavai/Vysledek
Description	An infrequent change to an otherwise repetitive sequence of stimuli leads to the generation of mismatch negativity (MMN), even in the absence of attention. This evoked negative response occurs in the scalp-recorded electroencephalogram (EEG) over the temporal and frontal cortices, 100–250 ms after onset of the deviant stimulus. The MMN is used to detect sensory information processing. The aim of our study was to investigate whether MMN can be recorded in the subthalamic nuclei (STN) as evidence of auditory information processing on an unconscious level within this structure. To our knowledge, MMN has never been recorded in the human STN. We recorded intracerebral EEG using a MMN paradigm in five patients with Parkinson’s disease (PD) who were implanted with depth electrodes in the subthalamic nuclei (STN). We found far-field MMN when intracerebral contacts were connected to an extracranial reference electrode. An infrequent change to an otherwise repetitive sequence of stimuli leads to the generation of mismatch negativity (MMN), even in the absence of attention. This evoked negative response occurs in the scalp-recorded electroencephalogram (EEG) over the temporal and frontal cortices, 100–250 ms after onset of the deviant stimulus. The MMN is used to detect sensory information processing. The aim of our study was to investigate whether MMN can be recorded in the subthalamic nuclei (STN) as evidence of auditory information processing on an unconscious level within this structure. To our knowledge, MMN has never been recorded in the human STN. We recorded intracerebral EEG using a MMN paradigm in five patients with Parkinson’s disease (PD) who were implanted with depth electrodes in the subthalamic nuclei (STN). We found far-field MMN when intracerebral contacts were connected to an extracranial reference electrode. (en)
Title	Mismatch negativity-like potential (MMN-like) in the subthalamic nuclei in Parkinson’s disease patients Mismatch negativity-like potential (MMN-like) in the subthalamic nuclei in Parkinson’s disease patients (en)
skos:prefLabel	Mismatch negativity-like potential (MMN-like) in the subthalamic nuclei in Parkinson’s disease patients Mismatch negativity-like potential (MMN-like) in the subthalamic nuclei in Parkinson’s disease patients (en)
skos:notation	RIV/00216224:14110/14:00074222!RIV15-MSM-14110___
http://linked.open...avai/riv/aktivita	I P Z
http://linked.open...avai/riv/aktivity	I, P(ED0017/01/01), P(ED1.1.00/02.0068), P(ED1.100/02/0123), P(GAP103/11/0933), P(LO1212), Z(MSM0021622404)
http://linked.open...iv/cisloPeriodika	12
http://linked.open...vai/riv/dodaniDat	2015
http://linked.open...aciTvurceVysledku	Chládek, Jan Bareš, Martin Chrastina, Jan Minks, Eduard Shaw, Daniel Joel
http://linked.open.../riv/druhVysledku	J - Článek v odborném periodiku
http://linked.open...iv/duvernostUdaju	S - Úplné a pravdivé údaje nepodléhající ochraně podle zvláštních právních předpisů
http://linked.open...titaPredkladatele	Masarykova univerzita / Lékařská fakulta
http://linked.open...dnocenehoVysledku	29521
http://linked.open...ai/riv/idVysledku	RIV/00216224:14110/14:00074222
http://linked.open...riv/jazykVysledku	eng - angličtina
http://linked.open.../riv/klicovaSlova	Intracranial electrodes; Mismatch negativity; MMN; MMN-like; STN; Subthalamic nucleus (en)
http://linked.open.../riv/klicoveSlovo	Intracranial electrodes MMN MMN-like Mismatch negativity Subthalamic nucleus STN
http://linked.open...odStatuVydavatele	AT - Rakouská republika
http://linked.open...ontrolniKodProRIV	[C382254F71D9]
http://linked.open...i/riv/nazevZdroje	Journal of Neural Transmission
http://linked.open...in/vavai/riv/obor	FH
http://linked.open...ichTvurcuVysledku	5 (xsd:int)
http://linked.open...cetTvurcuVysledku	7 (xsd:int)
http://linked.open...vavai/riv/projekt	ALISI - Centre of advanced diagnostic methods and technologies APPLICATION LABORATORIES OF ADVANCED MICROTECHNOLOGIES AND NANOTECHNOLOGIES Central european institute of technology Analysis of EEG Signals Scanned at High Frequencies from Deep Brain Structures St. Anne´s University Hospital Brno - International Clinical Research Center (FNUSA-ICRC)
http://linked.open...UplatneniVysledku	2014
http://linked.open...v/svazekPeriodika	121
http://linked.open...iv/tvurceVysledku	Bareš, Martin Chládek, Jan Halámek, Josef Jurák, Pavel Chrastina, Jan Minks, Eduard Shaw, Daniel Joel
http://linked.open...ain/vavai/riv/wos	000345409000005
http://linked.open...n/vavai/riv/zamer	The Internal Organisation and Neurobiological Mechanisms of Functional CNS Systems under Normal and Pathological Conditions
issn	0300-9564
number of pages	16 (xsd:int)
http://bibframe.org/vocab/doi	10.1007/s00702-014-1221-3
http://localhost/t...ganizacniJednotka	14110

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