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Description
| - The objective of this research was to determine whether invasively measured central pulse pressure (PP) in patients indicated for coronarography is associated with two common polymorphisms in the ACE2 region (rs4646156 and rs4646174). Methods: A total of 307 patients were enrolled in the study. The genotyping of both SNPs from peripheral blood samples was carried out using 5-exonuclease (Taqman) chemistry on the ABI Prism 7000 system (Applied Biosystems, Foster City, CA, USA). Results: In both polymorphisms, the associations with central PP were found to be highly significant when all five possible genotypes in the population had been compared (p = 0.0001). In men, there was a higher incidence of previous myocardial infarction in G0 genotype carriers of rs54646174 (OR ratio = 7; p = 0.005). The AA genotype of rs4646156 had a 7.81 higher risk of severe angina pectoris in women (OR = 7.81, p = 0.05).
- The objective of this research was to determine whether invasively measured central pulse pressure (PP) in patients indicated for coronarography is associated with two common polymorphisms in the ACE2 region (rs4646156 and rs4646174). Methods: A total of 307 patients were enrolled in the study. The genotyping of both SNPs from peripheral blood samples was carried out using 5-exonuclease (Taqman) chemistry on the ABI Prism 7000 system (Applied Biosystems, Foster City, CA, USA). Results: In both polymorphisms, the associations with central PP were found to be highly significant when all five possible genotypes in the population had been compared (p = 0.0001). In men, there was a higher incidence of previous myocardial infarction in G0 genotype carriers of rs54646174 (OR ratio = 7; p = 0.005). The AA genotype of rs4646156 had a 7.81 higher risk of severe angina pectoris in women (OR = 7.81, p = 0.05). (en)
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Title
| - ACE2 gene polymorphisms and invasively measured central pulse pressure in cardiac patients indicated for coronarography
- ACE2 gene polymorphisms and invasively measured central pulse pressure in cardiac patients indicated for coronarography (en)
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skos:prefLabel
| - ACE2 gene polymorphisms and invasively measured central pulse pressure in cardiac patients indicated for coronarography
- ACE2 gene polymorphisms and invasively measured central pulse pressure in cardiac patients indicated for coronarography (en)
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skos:notation
| - RIV/00216224:14110/13:00065567!RIV14-MZ0-14110___
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http://linked.open...avai/predkladatel
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http://linked.open...avai/riv/aktivita
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http://linked.open...avai/riv/aktivity
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http://linked.open...iv/cisloPeriodika
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http://linked.open...vai/riv/dodaniDat
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http://linked.open...aciTvurceVysledku
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http://linked.open.../riv/druhVysledku
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http://linked.open...iv/duvernostUdaju
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http://linked.open...titaPredkladatele
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http://linked.open...dnocenehoVysledku
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http://linked.open...ai/riv/idVysledku
| - RIV/00216224:14110/13:00065567
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http://linked.open...riv/jazykVysledku
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http://linked.open.../riv/klicovaSlova
| - ACE2; polymorphism; pulse pressure; severity (en)
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http://linked.open.../riv/klicoveSlovo
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http://linked.open...odStatuVydavatele
| - US - Spojené státy americké
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http://linked.open...ontrolniKodProRIV
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http://linked.open...i/riv/nazevZdroje
| - Journal of the Renin-Angiotensin-Aldosterone System
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http://linked.open...in/vavai/riv/obor
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http://linked.open...ichTvurcuVysledku
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http://linked.open...cetTvurcuVysledku
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http://linked.open...vavai/riv/projekt
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http://linked.open...UplatneniVysledku
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http://linked.open...v/svazekPeriodika
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http://linked.open...iv/tvurceVysledku
| - Bienertová Vašků, Julie
- Kala, Petr
- Pařenica, Jiří
- Vašků, Anna
- Zlámal, Filip
- Špinar, Jindřich
- Lipková, Jolana
- Pávková Goldbergová, Monika
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http://linked.open...ain/vavai/riv/wos
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issn
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number of pages
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http://bibframe.org/vocab/doi
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http://localhost/t...ganizacniJednotka
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