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Description
| - Sjögrenův syndrom je chronické systémové autoimunitní zánětlivé onemocnění postihující především slzné a slinné žlázy. Projevuje se tzv. sicca syn. Gastrointestinální postižení je časté jak u primárního, tak i u sekundárního Sjögrenova syndromu, po sicca syndromu a revmatologickém postižení je třetí nejčastější. Dysfagie je častým steskem nemocných se Sjögrenovým syndromem. Nejčastěji je způsobena nedostatkem slin, ale může být způsobena i dysmotilitní jícnovou poruchou. Chronická gastritida je přítomna až u 80 % pacientů se Sjögrenovým syndromem, tedy dvakrát častěji než u stejně starých osob všeobecné populace. Předpokládá se, že autoimunitní proces je hlavním patogenetickým mechanismem chronické gastritidy u Sjögrenova syndromu. Sjögrenův syndrom se také častěji spojuje s celiakií, a to jak s klinicky manifestní, tak i se silentní formou onemocnění. Významná je také asociace Sjögrenova syndromu a primární biliární cirhózy nebo chronické aktivní autoimunitní hepatitidy. (cs)
- Sjögren’s syndrome is a multi-system chronic autoimmune inflammatory disorder characterized primarily by diminished lacrimal and salivary gland secretion resulting in sicca syndrome. Gastrointestinal involvement is often seen both in primary and secondary Sjögren’s syndrome, being the third most frequent, after sicca syndrome and rheumatologic involvement. Dysphagia is a common symptom in Sjögren’s syndrome. This is most often due to lack of saliva but there have been also reports of oesophageal dysmotility. Chronic gastritis is found in up to 80 % Sjögren’s syndrome, which means as much as twice higher when compared with age-matched subjects. The autoimmune mechanism is considered to be the major factor in development of chronic gastritis in Sjögren’s syndrome. Sjögren’s syndrome can also be associated with coeliac disease, both symptomatic (active) and silent. There is a marked association of Sjögren’s syndrome to primary biliary cirrhosis and chronic active autoimmune hepatitis.
- Sjögren’s syndrome is a multi-system chronic autoimmune inflammatory disorder characterized primarily by diminished lacrimal and salivary gland secretion resulting in sicca syndrome. Gastrointestinal involvement is often seen both in primary and secondary Sjögren’s syndrome, being the third most frequent, after sicca syndrome and rheumatologic involvement. Dysphagia is a common symptom in Sjögren’s syndrome. This is most often due to lack of saliva but there have been also reports of oesophageal dysmotility. Chronic gastritis is found in up to 80 % Sjögren’s syndrome, which means as much as twice higher when compared with age-matched subjects. The autoimmune mechanism is considered to be the major factor in development of chronic gastritis in Sjögren’s syndrome. Sjögren’s syndrome can also be associated with coeliac disease, both symptomatic (active) and silent. There is a marked association of Sjögren’s syndrome to primary biliary cirrhosis and chronic active autoimmune hepatitis. (en)
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Title
| - Sjögrenův syndrom - pohled gastroenterologa (cs)
- Sjögren´s syndrome - gastroenterologist´s point of view
- Sjögren´s syndrome - gastroenterologist´s point of view (en)
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skos:prefLabel
| - Sjögrenův syndrom - pohled gastroenterologa (cs)
- Sjögren´s syndrome - gastroenterologist´s point of view
- Sjögren´s syndrome - gastroenterologist´s point of view (en)
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skos:notation
| - RIV/00216208:11150/04:00004485!RIV08-MSM-11150___
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http://linked.open.../vavai/riv/strany
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http://linked.open...avai/riv/aktivita
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http://linked.open...avai/riv/aktivity
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http://linked.open...iv/cisloPeriodika
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http://linked.open...vai/riv/dodaniDat
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http://linked.open...aciTvurceVysledku
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http://linked.open.../riv/druhVysledku
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http://linked.open...iv/duvernostUdaju
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http://linked.open...titaPredkladatele
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http://linked.open...dnocenehoVysledku
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http://linked.open...ai/riv/idVysledku
| - RIV/00216208:11150/04:00004485
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http://linked.open...riv/jazykVysledku
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http://linked.open.../riv/klicovaSlova
| - Sjögren´s; syndrome; gastroenterologist´s; point; view (en)
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http://linked.open.../riv/klicoveSlovo
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http://linked.open...odStatuVydavatele
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http://linked.open...ontrolniKodProRIV
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http://linked.open...i/riv/nazevZdroje
| - Folia Gastroenterologica et Hepatologica
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http://linked.open...in/vavai/riv/obor
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http://linked.open...ichTvurcuVysledku
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http://linked.open...cetTvurcuVysledku
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http://linked.open...UplatneniVysledku
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http://linked.open...v/svazekPeriodika
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http://linked.open...iv/tvurceVysledku
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issn
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number of pages
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http://localhost/t...ganizacniJednotka
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