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  • Background: Acute rhinosinusitis (ARS) has been shown to significantly reduce patient quality of life (QoL). While the QoL in patients with chronic rhinosinusitis has been the subject of intensive research over the last decade, studies measuring the impact of ARS on patient QoL have remained relatively scarce. The aim of this study was to determine the relationship between the QoL and parameters suggestive of acute bacterial rhinosinusitis (C-reactive protein [CRP] levels and positive culture) and to see if measurement of the QoL could be used as an indicator for antibiotic treatment in ARS. Methods: Eighty patients with ARS were enrolled in the study. A novel QoL instrument for patients with ARS, called Measurement of Acute Rhinosinusitis (MARS) questionnaire, was given to patients at the time of diagnosis. We assessed patient QoL, obtained endoscopically guided cultures from the middle meatus, and measured levels of CRP. The relationship between QoL MARS scores (QoL-Mscores) and CRP was determined using a correlation coefficient. To compare QoL-Mscores, relative to culture-positive and culture-negative patients, the Student's t-test was used. Results: No correlation between the QoL, assessed using the MARS questionnaire, and positive middle meatus culture was demonstrated (P = 0.332). A weak correlation was found between QoL-Mscores and CRP values, with a correlation coefficient of 0.221 and P = 0.0498. Conclusion: No correlation between the QoL in ARS patients and positive culture was found in this study. The clinical significance of the correlation between QoL-Mscores and CRP values in the antibiotic decision making process needs further research.
  • Background: Acute rhinosinusitis (ARS) has been shown to significantly reduce patient quality of life (QoL). While the QoL in patients with chronic rhinosinusitis has been the subject of intensive research over the last decade, studies measuring the impact of ARS on patient QoL have remained relatively scarce. The aim of this study was to determine the relationship between the QoL and parameters suggestive of acute bacterial rhinosinusitis (C-reactive protein [CRP] levels and positive culture) and to see if measurement of the QoL could be used as an indicator for antibiotic treatment in ARS. Methods: Eighty patients with ARS were enrolled in the study. A novel QoL instrument for patients with ARS, called Measurement of Acute Rhinosinusitis (MARS) questionnaire, was given to patients at the time of diagnosis. We assessed patient QoL, obtained endoscopically guided cultures from the middle meatus, and measured levels of CRP. The relationship between QoL MARS scores (QoL-Mscores) and CRP was determined using a correlation coefficient. To compare QoL-Mscores, relative to culture-positive and culture-negative patients, the Student's t-test was used. Results: No correlation between the QoL, assessed using the MARS questionnaire, and positive middle meatus culture was demonstrated (P = 0.332). A weak correlation was found between QoL-Mscores and CRP values, with a correlation coefficient of 0.221 and P = 0.0498. Conclusion: No correlation between the QoL in ARS patients and positive culture was found in this study. The clinical significance of the correlation between QoL-Mscores and CRP values in the antibiotic decision making process needs further research. (en)
Title
  • The relationship of C-reactive protein levels and positive culture with quality of life in acute rhinosinusitis
  • The relationship of C-reactive protein levels and positive culture with quality of life in acute rhinosinusitis (en)
skos:prefLabel
  • The relationship of C-reactive protein levels and positive culture with quality of life in acute rhinosinusitis
  • The relationship of C-reactive protein levels and positive culture with quality of life in acute rhinosinusitis (en)
skos:notation
  • RIV/00216208:11120/15:43909390!RIV15-MSM-11120___
http://linked.open...avai/riv/aktivita
http://linked.open...avai/riv/aktivity
  • I
http://linked.open...iv/cisloPeriodika
  • January 27
http://linked.open...vai/riv/dodaniDat
http://linked.open...aciTvurceVysledku
http://linked.open.../riv/druhVysledku
http://linked.open...iv/duvernostUdaju
http://linked.open...titaPredkladatele
http://linked.open...dnocenehoVysledku
  • 392
http://linked.open...ai/riv/idVysledku
  • RIV/00216208:11120/15:43909390
http://linked.open...riv/jazykVysledku
http://linked.open.../riv/klicovaSlova
  • anti-bacterial agents; questionnaires; quality of life; endoscopy (en)
http://linked.open.../riv/klicoveSlovo
http://linked.open...odStatuVydavatele
  • NZ - Nový Zéland
http://linked.open...ontrolniKodProRIV
  • [EC1B730F12EA]
http://linked.open...i/riv/nazevZdroje
  • Patient Preference and Adherence
http://linked.open...in/vavai/riv/obor
http://linked.open...ichTvurcuVysledku
http://linked.open...cetTvurcuVysledku
http://linked.open...UplatneniVysledku
http://linked.open...v/svazekPeriodika
  • 9
http://linked.open...iv/tvurceVysledku
  • Hahn, Aleš
  • Schalek, Petr
  • Hornáčková, Zuzana
http://linked.open...ain/vavai/riv/wos
  • 000348433400002
issn
  • 1177-889X
number of pages
http://bibframe.org/vocab/doi
  • 10.2147/PPA.S76915
http://localhost/t...ganizacniJednotka
  • 11120
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