About: Randomized controlled trials of autologous hematopoietic stem cell transplantation for autoimmune diseases : the evolution from myeloablative to lymphoablative transplant regimens     Goto   Sponge   Distinct   Permalink

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Description
  • Práce popisuje randomizovanou kontrolovano studii autologních transplantací hematopoetických kmenových buněk pro autoimunitní onemocnění (cs)
  • Hematologists/oncologists initiated the use of autologous hematopoietic stem cell transplantation. (HSCT) as a treatment for severe autoimmune diseases beginning in the early 1990s. According to multicenter reports, this therapy has been plagued by a high rate of transplant-related mortality. However, transplantrelated mortality from different individual centers varies widely. We will review and discuss how the differences in philosophy, rationale, and design of these protocols affect treatment-related mortality, and we will compare how these differences have influenced ongoing or soonto-be-opened randomized controlled trials of autologous HSCT for patients with autoimmune diseases. In particular, we will emphasize the distinction between myeloablative and lymphoablative trials
  • Hematologists/oncologists initiated the use of autologous hematopoietic stem cell transplantation. (HSCT) as a treatment for severe autoimmune diseases beginning in the early 1990s. According to multicenter reports, this therapy has been plagued by a high rate of transplant-related mortality. However, transplantrelated mortality from different individual centers varies widely. We will review and discuss how the differences in philosophy, rationale, and design of these protocols affect treatment-related mortality, and we will compare how these differences have influenced ongoing or soonto-be-opened randomized controlled trials of autologous HSCT for patients with autoimmune diseases. In particular, we will emphasize the distinction between myeloablative and lymphoablative trials (en)
Title
  • Randomized controlled trials of autologous hematopoietic stem cell transplantation for autoimmune diseases : the evolution from myeloablative to lymphoablative transplant regimens
  • Randomized controlled trials of autologous hematopoietic stem cell transplantation for autoimmune diseases : the evolution from myeloablative to lymphoablative transplant regimens (en)
  • Randomizovaná kontrolovaná studie autologní transplantace hematopoetických kmenových buněk pro autoimunitní onemocnění : evoluce od myeloablativních k lymfoablativním transplantačním režimům (cs)
skos:prefLabel
  • Randomized controlled trials of autologous hematopoietic stem cell transplantation for autoimmune diseases : the evolution from myeloablative to lymphoablative transplant regimens
  • Randomized controlled trials of autologous hematopoietic stem cell transplantation for autoimmune diseases : the evolution from myeloablative to lymphoablative transplant regimens (en)
  • Randomizovaná kontrolovaná studie autologní transplantace hematopoetických kmenových buněk pro autoimunitní onemocnění : evoluce od myeloablativních k lymfoablativním transplantačním režimům (cs)
skos:notation
  • RIV/00216208:11120/06:00001236!RIV09-MSM-11120___
http://linked.open...avai/riv/aktivita
http://linked.open...avai/riv/aktivity
  • S
http://linked.open...iv/cisloPeriodika
  • 12
http://linked.open...vai/riv/dodaniDat
http://linked.open...aciTvurceVysledku
http://linked.open.../riv/druhVysledku
http://linked.open...iv/duvernostUdaju
http://linked.open...titaPredkladatele
http://linked.open...dnocenehoVysledku
  • 496404
http://linked.open...ai/riv/idVysledku
  • RIV/00216208:11120/06:00001236
http://linked.open...riv/jazykVysledku
http://linked.open.../riv/klicovaSlova
  • systemic lupus erythematosus; bone marrow transplantation; dose immunosuppressive therapy; collagen vascular disease; phase I, II; rheumatoid arthritis; multiple sclerosis; radiation therapy; t cells; Crohns disease (en)
http://linked.open.../riv/klicoveSlovo
http://linked.open...odStatuVydavatele
  • US - Spojené státy americké
http://linked.open...ontrolniKodProRIV
  • [207D25E9201B]
http://linked.open...i/riv/nazevZdroje
  • Arthritis and Rheumatism
http://linked.open...in/vavai/riv/obor
http://linked.open...ichTvurcuVysledku
http://linked.open...cetTvurcuVysledku
http://linked.open...UplatneniVysledku
http://linked.open...v/svazekPeriodika
  • 54
http://linked.open...iv/tvurceVysledku
  • Kozák, Tomáš
  • Arnold, R.
  • Snowden, J.
  • Varga, J.
  • Hiepe, F.
  • Loh, Y.
  • Slavin, S.
  • Patel, D. D.
  • Burt, R. K.
  • Marmont, A.
  • Oyama, Y.
  • Statkute, L.
  • Verda, L.
  • Barr, W. G.
  • Cohen, B. A.
  • Collier, D.
  • Craig, R. M.
  • Fasses, A.
  • Heslop, H.
  • Hintzen, RQ.
  • Krance, R.
  • Myint, H.
  • Rose, J. W.
  • Schuening, F.
  • Territo, M.
  • Traynor, A.
  • Voltarelli, J.
issn
  • 0004-3591
number of pages
http://localhost/t...ganizacniJednotka
  • 11120
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