About: Effect of memantine in Alzheimer's disease evaluated by visual-evoked potentials to pattern-reversal, motion-onset, and cognitive stimuli

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rdf:type	skos:Concept http://linked.opendata.cz/ontology/domain/vavai/Vysledek
Description	Visual evoked potentials (VEPs) to pattern-reversal and motion stimulation as well as visual cognitive potentials (ERPs) were examined in 17 patients with mild to moderate Alzheimer disease before onset of Memantin treatment and after 3 and 6 months of Memantine therapy. The electrophysiological tests were able to prove a significant beneficial effect of Memantine therapy in our group of patients. Improvement of ERPs (shortening of P300 peak latency by at least 20 ms) occurred in 42% of patients. On the other hand, Memantine therapy led in 52% of patients to transitory decline of motion processing (delay of N2 peak latency of the motion-onset VEPs by at least 10 ms after the first 3 months of therapy, followed by return to pre-therapy values in next 3 months). Visual evoked potentials (VEPs) to pattern-reversal and motion stimulation as well as visual cognitive potentials (ERPs) were examined in 17 patients with mild to moderate Alzheimer disease before onset of Memantin treatment and after 3 and 6 months of Memantine therapy. The electrophysiological tests were able to prove a significant beneficial effect of Memantine therapy in our group of patients. Improvement of ERPs (shortening of P300 peak latency by at least 20 ms) occurred in 42% of patients. On the other hand, Memantine therapy led in 52% of patients to transitory decline of motion processing (delay of N2 peak latency of the motion-onset VEPs by at least 10 ms after the first 3 months of therapy, followed by return to pre-therapy values in next 3 months). (en)
Title	Effect of memantine in Alzheimer's disease evaluated by visual-evoked potentials to pattern-reversal, motion-onset, and cognitive stimuli Effect of memantine in Alzheimer's disease evaluated by visual-evoked potentials to pattern-reversal, motion-onset, and cognitive stimuli (en)
skos:prefLabel	Effect of memantine in Alzheimer's disease evaluated by visual-evoked potentials to pattern-reversal, motion-onset, and cognitive stimuli Effect of memantine in Alzheimer's disease evaluated by visual-evoked potentials to pattern-reversal, motion-onset, and cognitive stimuli (en)
skos:notation	RIV/00179906:_____/10:10081326!RIV11-MZ0-00179906
http://linked.open...avai/riv/aktivita	V Z
http://linked.open...avai/riv/aktivity	V, Z(MSM0021620820)
http://linked.open...iv/cisloPeriodika	5
http://linked.open...vai/riv/dodaniDat	2011
http://linked.open...aciTvurceVysledku	Vališ, Martin
http://linked.open.../riv/druhVysledku	J - Článek v odborném periodiku
http://linked.open...iv/duvernostUdaju	S - Úplné a pravdivé údaje nepodléhající ochraně podle zvláštních právních předpisů
http://linked.open...titaPredkladatele	Fakultní nemocnice Hradec Králové
http://linked.open...dnocenehoVysledku	256054
http://linked.open...ai/riv/idVysledku	RIV/00179906:_____/10:10081326
http://linked.open...riv/jazykVysledku	eng - angličtina
http://linked.open.../riv/klicovaSlova	Memantine; ERP; motion; VEP; Alzheimer's disease (en)
http://linked.open.../riv/klicoveSlovo	VEP ERP motion Alzheimer's disease Memantine
http://linked.open...odStatuVydavatele	US - Spojené státy americké
http://linked.open...ontrolniKodProRIV	[464662AC15B8]
http://linked.open...i/riv/nazevZdroje	Journal of Clinical Neurophysiology
http://linked.open...in/vavai/riv/obor	FH
http://linked.open...ichTvurcuVysledku	1 (xsd:int)
http://linked.open...cetTvurcuVysledku	7 (xsd:int)
http://linked.open...UplatneniVysledku	2010
http://linked.open...v/svazekPeriodika	27
http://linked.open...iv/tvurceVysledku	Kremláček, Jan Kuba, Miroslav Kubová, Zuzana Langrová, Jana Vališ, Martin Szanyi, Jana Vít, František
http://linked.open...ain/vavai/riv/wos	000282362400005
http://linked.open...n/vavai/riv/zamer	The use of experimental and clinical models of metabolic processes, nutrition and pharmacotherapy for the advancement of knowledge, clinical practice and quality of life improvement
issn	0736-0258
number of pages	7 (xsd:int)
is http://linked.open...avai/riv/vysledek of	Effect of memantine in Alzheimer's disease evaluated by visual-evoked potentials to pattern-reversal, motion-onset, and cognitive stimuli Effect of memantine in Alzheimer's disease evaluated by visual-evoked potentials to pattern-reversal, motion-onset, and cognitive stimuli Effect of memantine in Alzheimer's disease evaluated by visual-evoked potentials to pattern-reversal, motion-onset, and cognitive stimuli

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