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  • Despite optimal primary treatment, with adequate surgery with or without adjuvant chemotherapy, 30%–50% of patients with colon cancer will relapse and die of their disease. The principal aim of follow-up programmes after curative resection of colorectal cancer is to improve survival (Gan et al., 2007). To achieve this goal, patients are screened for early recurrent disease with the intent of a second curative surgery. Patients with a history of colorectal cancer are also at risk to develop new primary colorectal cancers (CRC). The risk of development of new primary lesions has been estimated to 0,35% per year (Cali et al.,1993). Bouvier et al reported the incidence of metachronous cancer as being 1.8% at five years, 3.4% at 10 years, and 7.2% at 20 years with the greatest excess risk between one and five years post-surgery(Bouvier et al. 2008).
  • Despite optimal primary treatment, with adequate surgery with or without adjuvant chemotherapy, 30%–50% of patients with colon cancer will relapse and die of their disease. The principal aim of follow-up programmes after curative resection of colorectal cancer is to improve survival (Gan et al., 2007). To achieve this goal, patients are screened for early recurrent disease with the intent of a second curative surgery. Patients with a history of colorectal cancer are also at risk to develop new primary colorectal cancers (CRC). The risk of development of new primary lesions has been estimated to 0,35% per year (Cali et al.,1993). Bouvier et al reported the incidence of metachronous cancer as being 1.8% at five years, 3.4% at 10 years, and 7.2% at 20 years with the greatest excess risk between one and five years post-surgery(Bouvier et al. 2008). (en)
Title
  • Follow up and recurrence of colorectal cancer
  • Follow up and recurrence of colorectal cancer (en)
skos:prefLabel
  • Follow up and recurrence of colorectal cancer
  • Follow up and recurrence of colorectal cancer (en)
skos:notation
  • RIV/00064190:_____/12:#0000391!RIV13-MZ0-00064190
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  • 136895
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  • RIV/00064190:_____/12:#0000391
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  • chemotherapy; Colorectal Cancer (en)
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  • [BB5B2DF6AD9A]
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  • Colorectal Cancer - From Prevention to Patient Care
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  • Levý, Miroslav
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  • 10.5772/2443
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  • InTech
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  • 978-953-51-0028-7
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