About: Modulation of Estrogen Receptor-Dependent Reporter Construct Activation and G0/G1-S-Phase Transition by Polycyclic Aromatic Hydrocarbons in Human Breast Carcinoma MCF-7 Cells

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About: Modulation of Estrogen Receptor-Dependent Reporter Construct Activation and G0/G1-S-Phase Transition by Polycyclic Aromatic Hydrocarbons in Human Breast Carcinoma MCF-7 Cells Goto Sponge Distinct Permalink

An Entity of Type : http://linked.opendata.cz/ontology/domain/vavai/Vysledek, within Data Space : linked.opendata.cz associated with source document(s)

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rdf:type	skos:Concept http://linked.opendata.cz/ontology/domain/vavai/Vysledek
Description	Estrogenicity in vitro of fluoranthene, benzo[a]pyrene and benz[a]anthracene were determined in the MCF-7 mammary breast cancer cell line stablz traqnsfected with luciferase reporter gene controlled by estrogen receptor alpha. These aromatics significantly potentiated estrogen receptor-mediated activit of estradiol and stimulated G0/G1-S-phase transition in MCF-7 cells. Estrogenicity in vitro of fluoranthene, benzo[a]pyrene and benz[a]anthracene were determined in the MCF-7 mammary breast cancer cell line stablz traqnsfected with luciferase reporter gene controlled by estrogen receptor alpha. These aromatics significantly potentiated estrogen receptor-mediated activit of estradiol and stimulated G0/G1-S-phase transition in MCF-7 cells. (en)
Title	Modulation of Estrogen Receptor-Dependent Reporter Construct Activation and G0/G1-S-Phase Transition by Polycyclic Aromatic Hydrocarbons in Human Breast Carcinoma MCF-7 Cells Modulation of Estrogen Receptor-Dependent Reporter Construct Activation and G0/G1-S-Phase Transition by Polycyclic Aromatic Hydrocarbons in Human Breast Carcinoma MCF-7 Cells (en)
skos:prefLabel	Modulation of Estrogen Receptor-Dependent Reporter Construct Activation and G0/G1-S-Phase Transition by Polycyclic Aromatic Hydrocarbons in Human Breast Carcinoma MCF-7 Cells Modulation of Estrogen Receptor-Dependent Reporter Construct Activation and G0/G1-S-Phase Transition by Polycyclic Aromatic Hydrocarbons in Human Breast Carcinoma MCF-7 Cells (en)
skos:notation	RIV/00027162:_____/02:90000075!RIV/2003/MZE/M03003/N
http://linked.open.../vavai/riv/strany	193;201
http://linked.open...avai/riv/aktivita	P Z
http://linked.open...avai/riv/aktivity	P(GP525/01/D076), P(QC0194), Z(AV0Z5004920)
http://linked.open...iv/cisloPeriodika	2
http://linked.open...vai/riv/dodaniDat	2003
http://linked.open...aciTvurceVysledku	Machala, Miroslav
http://linked.open.../riv/druhVysledku	J - Článek v odborném periodiku
http://linked.open...iv/duvernostUdaju	S - Úplné a pravdivé údaje nepodléhající ochraně podle zvláštních právních předpisů
http://linked.open...titaPredkladatele	Výzkumný ústav veterinárního lékařství, v.v.i.
http://linked.open...dnocenehoVysledku	654052
http://linked.open...ai/riv/idVysledku	RIV/00027162:_____/02:90000075
http://linked.open...riv/jazykVysledku	eng - angličtina
http://linked.open.../riv/klicovaSlova	PAHs; MAPkinases; estrogenicity; cell cycle; (en)
http://linked.open.../riv/klicoveSlovo	estrogenicity PAHs MAPkinases cell cycle
http://linked.open...odStatuVydavatele	GB - Spojené království Velké Británie a Severního Irska
http://linked.open...ontrolniKodProRIV	[2A44745AF3CC]
http://linked.open...i/riv/nazevZdroje	Toxicological Sciences
http://linked.open...in/vavai/riv/obor	DN
http://linked.open...ichTvurcuVysledku	3 (xsd:int)
http://linked.open...cetTvurcuVysledku	3 (xsd:int)
http://linked.open...ocetUcastnikuAkce	0 (xsd:int)
http://linked.open...nichUcastnikuAkce	0 (xsd:int)
http://linked.open...vavai/riv/projekt	Biochemical markers of dioxin-like toxicity and further specific effects of xenobiotics Activation of MAP protein kinase pathways by polycyclic aromatic hydrocarbons in vitro - a potential nongenotoxic mechanism underlying the effects of environmen
http://linked.open...UplatneniVysledku	2002
http://linked.open...v/svazekPeriodika	70
http://linked.open...iv/tvurceVysledku	Machala, Miroslav
http://linked.open...n/vavai/riv/zamer	Biophysical properties of living systems and their changes under the influence of environmental factors
issn	1096-6080
number of pages	9 (xsd:int)

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