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Description
| - Článek na základě neurozobrazovacích studií nepostižených příbuzných bipolárních pacientů, pediatrické bipolární poruchy, pacientů s první epizodou a pacientů s rodinnou anamnézou bipolární poruchy pátrá po neuroanatomických změnách použitelných jako biologické markery pro bipolární poruchy. (cs)
- OBJECTIVE: Neuroimaging studies show structural brain abnormalities in bipolar patients. Some of the abnormalities may represent biological risk factors conveying vulnerability for the disease. This paper aims to identify neuroanatomical risk factors for bipolar disorder (BD). METHODS: We reviewed magnetic resonance imaging (MRI) findings in populations in which the effects of the disease or treatment are minimal or where the chances of finding genetically coded risk factors shared within the families are increased. Such populations include unaffected relatives of bipolar patients, first-episode patients, children or adolescents with BD and patients with familial BD. RESULTS: MEDLINE search revealed 30 relevant scientific papers. Abnormalities in the volume of the striatum, left hemispheric white matter, thalamus and anterior cingulate as well as quantitative MRI signal hyperintensities were identified already in unaffected relatives of bipolar patients. Subjects in the early stages of the disease sho
- OBJECTIVE: Neuroimaging studies show structural brain abnormalities in bipolar patients. Some of the abnormalities may represent biological risk factors conveying vulnerability for the disease. This paper aims to identify neuroanatomical risk factors for bipolar disorder (BD). METHODS: We reviewed magnetic resonance imaging (MRI) findings in populations in which the effects of the disease or treatment are minimal or where the chances of finding genetically coded risk factors shared within the families are increased. Such populations include unaffected relatives of bipolar patients, first-episode patients, children or adolescents with BD and patients with familial BD. RESULTS: MEDLINE search revealed 30 relevant scientific papers. Abnormalities in the volume of the striatum, left hemispheric white matter, thalamus and anterior cingulate as well as quantitative MRI signal hyperintensities were identified already in unaffected relatives of bipolar patients. Subjects in the early stages of the disease sho (en)
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Title
| - Neuroanatomical abnormalities as risk factors for bipolar disorder
- Neuroanatomical abnormalities as risk factors for bipolar disorder (en)
- Neuroanatomické změny jako rizikové faktory bipolární poruchy (cs)
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skos:prefLabel
| - Neuroanatomical abnormalities as risk factors for bipolar disorder
- Neuroanatomical abnormalities as risk factors for bipolar disorder (en)
- Neuroanatomické změny jako rizikové faktory bipolární poruchy (cs)
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skos:notation
| - RIV/00023752:_____/05:00000883!RIV09-MZ0-00023752
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http://linked.open...avai/riv/aktivita
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http://linked.open...avai/riv/aktivity
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http://linked.open...iv/cisloPeriodika
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http://linked.open...vai/riv/dodaniDat
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http://linked.open...aciTvurceVysledku
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http://linked.open.../riv/druhVysledku
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http://linked.open...iv/duvernostUdaju
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http://linked.open...titaPredkladatele
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http://linked.open...dnocenehoVysledku
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http://linked.open...ai/riv/idVysledku
| - RIV/00023752:_____/05:00000883
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http://linked.open...riv/jazykVysledku
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http://linked.open.../riv/klicovaSlova
| - adolescents; amygdala; bipolar disorder; children; hippocampus; magnetic resonance imaging; striatum; subgenual prefrontal cortes (en)
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http://linked.open.../riv/klicoveSlovo
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http://linked.open...odStatuVydavatele
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http://linked.open...ontrolniKodProRIV
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http://linked.open...i/riv/nazevZdroje
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http://linked.open...in/vavai/riv/obor
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http://linked.open...ichTvurcuVysledku
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http://linked.open...cetTvurcuVysledku
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http://linked.open...UplatneniVysledku
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http://linked.open...v/svazekPeriodika
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http://linked.open...iv/tvurceVysledku
| - Hájek, Tomáš
- Alda, M.
- Carrey, N.
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issn
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number of pages
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is http://linked.open...avai/riv/vysledek
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