About: Neuroscience Institute. Research of signal transmission in brain and spinal cord in physiological and pathological states

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An Entity of Type : http://linked.opendata.cz/ontology/domain/vavai/Projekt, within Data Space : linked.opendata.cz associated with source document(s)

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rdf:type	http://linked.opendata.cz/ontology/domain/vavai/Projekt
rdfs:seeAlso	http://www.isvav.cz/projectDetail.do?rowId=VS96130
Description	The aim of the project is to establish the Department of Neuroscience for basic and clinical research as well as for the teaching of pre- and postgraduate students. The main research concerns are: The function and membrane properties of glial cells. The role of glia in the ionic homeostasis. Changes in the function and membrane properties of glial cells during ischemia, inflammation, epilepsy, X-irradiation, aging, tumors and in transplanted tissue. he mechanisms of neuronal and glial swelling in normal and pathologically altered nervous tissue. The diffusion parameters of the brain and spinal cord. The diffusion properties of pathologically altered nervous tissue, studied by diffusion-weighted NMR. (en) Ústav neurověd budou tvořit neurofyziologické laboratoře, které budou zřízeny za účelem základního výzkumu přenosu signálů v mozku a míše během fyziologických a patologických stavů a za účelem školení pre- a postgraduálních studentů 2. LF a 3. LF. Základní výzkum bude propojen s klinickým.
Title	Neuroscience Institute. Research of signal transmission in brain and spinal cord in physiological and pathological states (en) Ústav neurověd. Výzkum přenosu signálů v mozku a v míše během fyziologických a patologických stavů
skos:notation	VS96130
http://linked.open...avai/cep/aktivita	Strengthening of research at the universities
http://linked.open...kovaStatniPodpora	http://linked.opendata.cz/resource/domain/vavai/projekt/VS96130/celkovaStatniPodpora
http://linked.open...ep/celkoveNaklady	http://linked.opendata.cz/resource/domain/vavai/projekt/VS96130/celkoveNaklady
http://linked.open...ep/duvernostUdaju	S - Úplné a pravdivé údaje nepodléhající ochraně podle zvláštních právních předpisů
http://linked.open.../cep/fazeProjektu	601148
http://linked.open...ai/cep/hlavniObor	ED - Fyziologie
http://linked.open...hodnoceniProjektu	U - Uspěl podle zadání, tj. byly splněny cíle a jeho předpokládané výsledky uvedené ve smlouvě / rozhodnutí o poskytnutí podpory
http://linked.open.../cep/klicovaSlova	neuroscience, glial cells, ionic homeostasis, ischemia, epilepsy, aging, transplanted nervous tissue (en)
http://linked.open...ep/partnetrHlavni	2. lékařská fakulta
http://linked.open...inujicichPrijemcu	0 (xsd:int)
http://linked.open...cep/pocetPrijemcu	1 (xsd:int)
http://linked.open...ocetSpoluPrijemcu	0 (xsd:int)
http://linked.open.../pocetVysledkuRIV	46 (xsd:int)
http://linked.open...enychVysledkuVRIV	46 (xsd:int)
http://linked.open...iciPoslednihoRoku	2001
http://linked.open...atUdajeProjZameru	2001
http://linked.open...usZobrazovaneFaze	DUU
http://linked.open...ai/cep/typPojektu	P - Projekt výzkumu a vývoje financovaný ze státního rozpočtu
http://linked.open.../cep/vedlejsiObor	FA - Kardiovaskulární nemoci včetně kardiochirurgie FL - Psychiatrie, sexuologie
http://linked.open...jektu+dodavatelem	Ústav neurověd UK je zaměřen na: nesynaptický přenos, funkci a membr. vlastnosti nervových buněk a jejich změny během patologických stavů, úlohu glie v iontové homeostáze, difúzní vlastnosti nervové tkáně během fyziolog. funkcí a onemocnění mozku apod. (cs)
http://linked.open...tniCyklusProjektu	ZBBBKU
http://linked.open.../cep/klicoveSlovo	neuroscience aging ischemia epilepsy glial cells ionic homeostasis
is http://linked.open...vavai/riv/projekt of	Glia and Extracellular Space Diffusion Parameters in the Injured and Aging Brain. Glial diffusion barriers during aging and pathological states. Extracellular space volume fraction and geometry in human cortex and glial tumors. Effects of Nitric Oxide Inhibition on the Spread of Biotinylated Dextran and on Extracullular Space Parameters in the Neostriatum of the Male Rat Diffusion Barriers Evoked in the Rat Cortex by Reactive Astrogliosis. Membrane Properties of Glial Cells in the Central Nervous System Volume transmission in the CNS and its relevance for neuropsychopharmacology. Changes of extracellular space diffusion parameters in the rat brain following induction of hydrocephalus. Extracellular diffusion parametrs in spinal cord and filum terminale of the frog. Glial influence on neuronal signaling. Extracellular space diffusion and pathological states. Extracellular Diffusion Parameters in Spinal Cord and Filum Terminale of the Frog. Glial diffusion barriers during aging and pathological states. Extracellular space diffusion parameters in human cortex and gliomas. Extracellular space diffusion parameters in tissue slices of human cortex and glial tumors. Extracellular matrix and diffusion barriers in the extracellular space. Extracellular space diffusion parameters in rat auditory cortex after injury. Extracellular diffusion in the striatum of 6-ohda - lesioned and grafted rats. Extracellular space volume fraction and geometry in human cortex and gliomas. Glial cells and volume transmission in the CNS. Membrane properties of astrocytes and extracellular space diffusion parameters in gray matter of spinal cord slices in GFAP-/-mice during cell swelling. Membrane currents of neurons and glia, and extracellulat space diffusion parameters in spinal cord and filum terminale of the frog. MRS and diffusion changes in a rat model of traumatic injury. Swelling and membrane properties of astrocytes in spinal cord of GEAP - deficient mice. Poly [N-(2hydroxypropyl) methacrylamide] Polymers Diffuse in Brain Extracellular Space with Same Tortuosity as Small Molecules. Changes in Extracellular Space Volume and Geometry Induced by Cartical Spreading Depression in Immature and Adult Rats Glutamate, kainate and N-methyl-D-aspartate-evoked membrane currents in identified glial cells in rat spinal cord slice. Astrocytes, oligodendroglia, extracellular space volume and geometry in rat fetal brain grafts. Glial Depolarization Evokes a Larger Potassium Accumulation Around Oligodendrocytes Than Around Oligodendrocytes of Rat Spinal Cord Slices Glial swelling and astrogliosis produce diffusion barriers in the rat spinal cord. Neural Tissue Formation Within Porous Hydrogels Implanted in Brain and Spinal Cord Lesions: Ultrastructural, Immunohistochemical, and Diffusion Studies. Absence of GEAP affects astrocytic swelling and extracellular space diffusion parameters in mouse cortex. Altered diffusion parameters in adult rats with kaolininduced hydrocephalus. A mathematical model of K+ accumulation in the vicinity of astrocytes and oligodendrocytes in the rat spinal cord. Effect if glutamate on extracellular space diffusion parameters, K+ and ph in the isolated rat spinal cord. Diffusion of PHPMA polymers in brain extracellular space. Long distance signalling in volume transmission. Focus on clearance mechanism. Intrinsic optical signals evoked in spinal cord slices and their relation to neural activity and cell swelling. Volume transmission revisited Biocompatible polymer hydrogels usable for nervous tissue regeneration. Changes in astrocytic structure in rat hippocampus evoked by activation of glutamate receptors and learning. Caveolae are involved in the trafficing of mouse polyomavirus virions and artificial VP1 pseudocapsids toward cell nuclei. Changes in glial K+ currents with decreased cextracellular volume in developing rat white matter. Effect of Osmotic Stress on Potasssium Accumulation Around Glial Cells and Extracellular Space Volume in Rat Spinal Cord Slices. Diffusion and MRS in a rat cortex after traumatic injury. MR in phenylketonuria-related brain lesions.
is http://linked.open...vavai/cep/projekt of	http://linked.opendata.cz/resource/domain/vavai/cep/ucast/VS96130/1996/ico%3A00064203 http://linked.opendata.cz/resource/domain/vavai/cep/ucast/VS96130/1996/orjk%3A11120 http://linked.opendata.cz/resource/domain/vavai/cep/ucast/VS96130/1996/orjk%3A11130 http://linked.opendata.cz/resource/domain/vavai/cep/ucast/VS96130/1997/ico%3A00064203 http://linked.opendata.cz/resource/domain/vavai/cep/ucast/VS96130/1997/orjk%3A11120 http://linked.opendata.cz/resource/domain/vavai/cep/ucast/VS96130/1997/orjk%3A11130 http://linked.opendata.cz/resource/domain/vavai/cep/ucast/VS96130/1998/ico%3A00216208 http://linked.opendata.cz/resource/domain/vavai/cep/ucast/VS96130/1999/orjk%3A11130 http://linked.opendata.cz/resource/domain/vavai/cep/ucast/VS96130/2000/orjk%3A11130 http://linked.opendata.cz/resource/domain/vavai/cep/ucast/VS96130/2001/orjk%3A11130

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