About: Genetic basis of syndrome MIA (Malnutrition - Inflammation - Atherosclerosis) - complication of hemodialysis treatment     Goto   Sponge   Distinct   Permalink

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Description
  • To characterise genotype frequencies of ghrelin, LBP and HFE genes in patients with chronic renal failure and/or syndrome MIA and in control population. To analyse, if ghrelin, LBP and HFE gene variants influence complications of hemodialysis treatment, and incidence of cardiovascular disease in patients with chronic renal failure and/or syndrome MIA. (en)
  • Charakterizovat na pacientech s chronickým renálním selháním a MIA syndromem frekvence alel a genotypů genů pro ghrelin, LBP a HFE a zjistit, zda se liší od výskytu alel v populaci. Zjistit, jak varianty genů pro ghrelin, LBP a HFE ovlivní komplikace hemodialyzační léčby a incidenci kardiovaskulárních onemocnění u pacientů s chronickým renálním selháním a MIA syndromem.
Title
  • Genetic basis of syndrome MIA (Malnutrition - Inflammation - Atherosclerosis) - complication of hemodialysis treatment (en)
  • Genetická podstata komplikace hemodialyzační léčby - syndromu MIA (Malnutrition-Inflammation-Atherosclerosis)
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  • NR7958
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  • Dialysis; Ghrelin; LBP; Polymorphism; HFE; DNA; Atherosclerosis; Renal failure (en)
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  • Analyzováno 16 varisnt v 8 genech pro riziko renálního selhání či kompilací hemodialyzační léčby. Vztah prokázán u APOE, HFE, FTO, MTHFR. Gen pro ghrelin ovlivnil vývoj cholesterolu a BMI. (cs)
  • Altogether 16 variants in 8 genes were analyzed as putative risk factors for renal failure and/or hemodialysis complications. Renal failure was associated with variants APOE, HFE, FTO, MTHFR. Ghrelin variants had effect on cholesterol a BMI development. (en)
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  • Dialysis
  • DNA
  • Atherosclerosis
  • Ghrelin
  • HFE
  • LBP
  • Polymorphism
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