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  • Familiární kombinovaná hyperlipidemie: korelace polymorfismů vybraných genů s fenotypickým lipidovým vyjádřením, známkami inzulínové rezistence, trombogenními markery a morfologickými projevy časné aterosklerózy.
  • Familial combined hyperlipidemia: correlation of some polymorphism of the %22modifier%22 candidate genes with lipoprotein phenotypes, markers of insulin resistance, thrombogenic markers and with morphological signs of early atherosclerosis. Examination of the following polymorphisms: lipoprotein lipase - Asp9Asn, Asn291Ser, Ser447term; Apo CIII/SstI, Apo AI/MspI; CETP/Taq1B; hepatic lipase G-250A; common polymorphim of apo E; Apo B: XbaI and Eco RI. Evaluation of the intima-media thickness and of endothelial dysfunction by high-resolution B-mode ultrasound. (en)
Title
  • Familial combined hyperlipidemia: correlation of genetic (DNA) and biochemical markers with morphological signs of early atherosclerosis (en)
  • Familiární kombinovaná hyperlipidemie: korelace genetických (DNA) a biochemických markerů s morfologickými znaky časné aterosklerózy
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  • NB6563
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  • hyperlipidemia;familial;genetics;atherosclerosis;intima-media thickness;endothelial dysfunction;insulin resistance;thrombosis (en)
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  • Nové poznatky o významu některých laboratorních ukazatelů v časných stádiích aterosklerózy. Dále byly na pracovišti zavedeny nové metody včetně analýz kandidátních genů. (cs)
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  • atherosclerosis
  • insulin resistance
  • endothelial dysfunction
  • genetics
  • intima-media thickness
  • hyperlipidemia
  • familial
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